A more intensive approach to diagnosis and management of asthma in primary care: a randomised controlled trial
| ISRCTN | ISRCTN08067387 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN08067387 |
| Secondary identifying numbers | 03/050 |
- Submission date
- 13/07/2006
- Registration date
- 17/08/2006
- Last edited
- 25/10/2022
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Respiratory
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Dominick Shaw
Scientific
Scientific
17 Arleston Drive
Wollaton
Nottingham
NG8 2FR
United Kingdom
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Other |
| Study type | Treatment |
| Scientific title | A more intensive approach to diagnosis and management of asthma in primary care: a randomised controlled trial |
| Study objectives | Use of exhaled nitric oxide will result in fewer asthma exacerbations. |
| Ethics approval(s) | University Hospitals of Leicester (ref. no.: 9141) and the Leicester Primary Research Care Alliance (ref. no.: 0274). |
| Health condition(s) or problem(s) studied | Asthma |
| Intervention | Titrate steroid dose on basis of exhaled nitric oxide versus control group receiving treatment as per current BTS (British Thoracic Society) guidelines. |
| Intervention type | Drug |
| Pharmaceutical study type(s) | |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | Nitric oxide |
| Primary outcome measure | Asthma exacerbations. |
| Secondary outcome measures | Steroid dose (area under curve). |
| Overall study start date | 01/01/2004 |
| Completion date | 01/01/2006 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Lower age limit | 18 Years |
| Upper age limit | 85 Years |
| Sex | Both |
| Target number of participants | 200 |
| Key inclusion criteria | 1. Asthma 2. On treatment, providing it is a repeat prescription i.e., the patient suffers from chronic asthma 3. Aged 18-85 |
| Key exclusion criteria | Recent exacerbation |
| Date of first enrolment | 01/01/2004 |
| Date of final enrolment | 01/01/2006 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
17 Arleston Drive
Nottingham
NG8 2FR
United Kingdom
NG8 2FR
United Kingdom
Sponsor information
Asthma UK (UK)
Charity
Charity
Summit House
70 Wilson Street
London
EC2A 2DB
United Kingdom
| Website | http://www.asthma.org.uk/ |
|---|---|
"ROR" |
https://ror.org/03z7xev21 |
Funders
Funder type
Charity
Asthma UK
Private sector organisation / Other non-profit organizations
Private sector organisation / Other non-profit organizations
- Alternative name(s)
- Asthma UK, Asthma + Lung UK
- Location
- United Kingdom
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan | Not provided at time of registration |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | 01/08/2007 | Yes | No |
Editorial Notes
25/10/2022: Internal review.
