Condition category
Respiratory
Date applied
15/10/2002
Date assigned
15/10/2002
Last edited
09/10/2007
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Mr Samuel Coenen

ORCID ID

Contact details

Centre for General Practice
University of Antwerp
Universiteitsplein 1
Antwerp
B-2610
Belgium
+32 (0)3 820 25 25
samuel.coenen@ua.ac.be

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N/A

Study information

Scientific title

Acronym

Study hypothesis

This study aims to establish a valid estimate of the effect of perceived patient demand on General Practitioners (GPs) antibiotic prescribing, specifically for patients consulting with acute cough as one of the most prominent complaints, and to contribute to the necessary understanding of this complex prescription decision.

Ethics approval

This study was approved by the medical ethics committee of the University of Antwerp (A99-088).

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

GP practices

Trial type

Treatment

Patient information sheet

Condition

Acute cough

Intervention

Only the GPs in the intervention group received our guideline for the management of acute cough, followed by an educational outreach visit to discuss the implementation of the guideline and a postal reminder with the key message of the guideline.

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

The antibiotic prescribing rate by GPs for adult patients with acute cough.

Secondary outcome measures

1. Type of antibiotics prescribed, if any
2. Change in antibiotic prescribing affecting symptom resolution

Overall trial start date

01/01/2000

Overall trial end date

01/01/2002

Reason abandoned

Eligibility

Participant inclusion criteria

Flemish GPs randomised participants into an intervention and a control group including:
1. Immunocompetent patients
2. Aged 18 - 65 years old
3. With a new or worsening cough present for less than 30 days as (one of the) most prominent complaint(s) and as the reason for a first encounter at the GPs practice

Participant type

Patient

Age group

Adult

Gender

Both

Target number of participants

85 Flemish GPs

Participant exclusion criteria

Not provided at time of registration

Recruitment start date

01/01/2000

Recruitment end date

01/01/2002

Locations

Countries of recruitment

Belgium

Trial participating centre

Centre for General Practice
Antwerp
B-2610
Belgium

Sponsor information

Organisation

University of Antwerp (Belgium)

Sponsor details

Centre for General Practice
Universiteitsplein 1
Antwerp
B-2610
Belgium

Sponsor type

University/education

Website

http://www.ua.ac.be/

Funders

Funder type

Research organisation

Funder name

Fund for Scientific Research, Flanders (Belgium) - Samuel Coenen was research assistant

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

The Scientific Society of Flemish General Practitioners (Belgium) - funded the development of the guideline for the management of acute cough

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Results in http://www.ncbi.nlm.nih.gov/sites/entrez?db=PubMed&cmd=Retrieve&list_uids=16536958

Publication citations

  1. Results

    Coenen S, Michiels B, Renard D, Denekens J, Van Royen P, Antibiotic prescribing for acute cough: the effect of perceived patient demand., Br J Gen Pract, 2006, 56, 524, 183-190.

Additional files

Editorial Notes