Stop Stroke: The South London Secondary Prevention Programme

ISRCTN	ISRCTN10730637
DOI	https://doi.org/10.1186/ISRCTN10730637
Secondary identifying numbers	1824/1845

Submission date: 19/07/2005
Registration date: 07/09/2005
Last edited: 07/12/2010

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Circulatory System

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Prof Charles Wolfe
Scientific

Division of Health & Social Care Research
King's College London
7th Floor Capital House
42 Weston Street
London
SE1 3QD
United Kingdom

Phone	+44 (0)20 7848 6608
Email	charles.wolfe@kcl.ac.uk

Study information

Study design	Randomised controlled trial
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Not specified
Study type	Prevention
Scientific title
Study acronym	Stop Stroke
Study objectives	To test the efficacy of a complex secondary prevention intervention on improving post stroke risk factor control. The study uses a cluster randomised controlled trial design with 120 general practices randomised at the start of the trial. All participants at a given practice (patients, carers and primary care staff) receive either the intervention or usual care.
Ethics approval(s)	Not provided at time of registration.
Health condition(s) or problem(s) studied	Stroke
Intervention	Intervention: Computer algorithms are used to systematically transform data collected by an ongoing stroke register (SLSR) into individually tailored secondary prevention plans for patients, carers and the primary care team. The plans include details of the patient's current risk factor control and evidence based advice on how to improve risk factor management. Plans are updated and distributed at three time points. Control: Usual care.
Intervention type	Other
Primary outcome measure	Prevalence of uncontrolled key modifiable risk factors for stroke (hypertension, smoking, aspirin adherence) measured at one year post stroke.
Secondary outcome measures	Prevalence of other uncontrolled risk factors for stroke (cholesterol, diabetes, atrial fibrillation, obesity, heavy drinking); stroke recurrence rate.
Overall study start date	21/07/2003
Completion date	01/01/2007

Eligibility

Participant type(s)	Patient
Age group	Adult
Sex	Both
Target number of participants	450 patients
Key inclusion criteria	All patients with a diagnosis of first-in-a-lifetime stroke living in Lambeth and Southwark.
Key exclusion criteria	Patients must be alive six weeks post stroke, identified by the study team within six months of stroke and registered with a general practitioner.
Date of first enrolment	21/07/2003
Date of final enrolment	01/01/2007

Locations

Countries of recruitment

England
United Kingdom

Study participating centre

Division of Health & Social Care Research

London
SE1 3QD
United Kingdom

Sponsor information

King's College London (UK)
University/education

Division of Health and Social Care Research
7th Floor Capital House
42 Weston Street
London
SE1 3QD
England
United Kingdom

Phone	+44 (0)207848 6651/4113
Email	lesley.higgins@kcl.ac.uk
Website	http://www.kcl.ac.uk
"ROR"	https://ror.org/0220mzb33

Funders

Funder type

Not defined

The Health Foundation 1824/1845,

No information available

The Stroke Association TSA G1,

No information available

Medical Research Council Special Training Fellowship Award G106/1105, Department of Health Career Scientist Award PHCSA02/07.

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

Study outputs

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	01/11/2010		Yes	No