Condition category
Cancer
Date applied
06/04/2000
Date assigned
06/04/2000
Last edited
27/07/2009
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Prof JH Scholefield

ORCID ID

Contact details

Section of Surgery
Floor E
West Block
Queen's Medical Centre
Nottingham
NG7 2UH
United Kingdom

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

G8317732/G9826520

Study information

Scientific title

Acronym

Study hypothesis

Demonstrate possible reduction in mortality from screening for colorectal cancer

Ethics approval

Not provided at time of registration.

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Not Specified

Patient information sheet

Condition

Cancer

Intervention

Haemoccult faecal occult blood screening test/control

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Not provided at time of registration.

Secondary outcome measures

Not provided at time of registration.

Overall trial start date

01/01/1984

Overall trial end date

30/09/2009

Reason abandoned

Eligibility

Participant inclusion criteria

Population aged 50-74 years (June 06: changed from 50-75 years)

Participant type

Patient

Age group

Not Specified

Gender

Not Specified

Target number of participants

152,000

Participant exclusion criteria

Colorectal cancer within 5 yrs of entry date/GPs discretion

Recruitment start date

01/01/1984

Recruitment end date

30/09/2009

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Section of Surgery
Nottingham
NG7 2UH
United Kingdom

Sponsor information

Organisation

Medical Research Council (MRC) (UK)

Sponsor details

20 Park Crescent
London
W1B 1AL
United Kingdom
+44 20 7636 5422
clinical.trial@headoffice.mrc.ac.uk

Sponsor type

Research council

Website

http://www.mrc.ac.uk

Funders

Funder type

Government

Funder name

Medical Research Council (UK)

Alternative name(s)

MRC

Funding Body Type

private sector organisation

Funding Body Subtype

other non-profit

Location

United Kingdom

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

1. 1996 results in http://www.ncbi.nlm.nih.gov/pubmed/8942775
2. 2002 results in http://www.ncbi.nlm.nih.gov/pubmed/12010887

Publication citations

  1. Results

    Hardcastle JD, Chamberlain JO, Robinson MH, Moss SM, Amar SS, Balfour TW, James PD, Mangham CM, Randomised controlled trial of faecal-occult-blood screening for colorectal cancer., Lancet, 1996, 348, 9040, 1472-1477, doi: 10.1016/S0140-6736(96)03386-7.

  2. Results

    Scholefield JH, Moss S, Sufi F, Mangham CM, Hardcastle JD, Effect of faecal occult blood screening on mortality from colorectal cancer: results from a randomised controlled trial., Gut, 2002, 50, 6, 840-844.

Additional files

Editorial Notes