Plain English Summary
Background and study aims
Education and exercise have been recommended for patients with knee osteoarthritis (OA). However, due to the chronic nature of pain of knee OA as well as the difficulty in access to health services, patients would benefit from a self-managed programme that encourages physical activity.
Who can participate?
Patients with knee OA, with no cognitive issues
What does the study involve?
It involves a web-based rehabilitation programme (combining both behavioural and exercise components) as well as suggested specified walk journeys within their municipality.
What are the potential benefits and risks of participating?
Patients would learn how to manage their pain with confidence and be more physically active. No real risks associated, apart from the discomfort that might arise after undertaking an exercise programme lasting for 2-3 days.
Where is the study run from?
University of West Attica (Greece)
When is the study starting and how long is it expected to run for?
February 2020 to February 2022
Who is funding the study?
State Foundation Scholarship (IKY) (Greece)
Who is the main contact?
The effects of self-managed web-based rehabilitation versus monitored physical activity on levels of pain, functionality and quality of life in patients with knee osteoarthritis
Web-based rehabilitation is superior to monitored physical activity in pain levels and functionality in patients with knee osteoarthritis.
Approved 20/07/2020, Research Ethics Committee of the University of West Attica (Ag Spiridonos, Egaleo, PC 12243, Greece; +30 3105387294; firstname.lastname@example.org), ref: 49238/09-07-20
Double-blind randomized controlled trial
Primary study design
Secondary study design
Randomised controlled trial
Quality of life
Patient information sheet
Not available in web format. please use contact details to request a participant information sheet.
Group 1: This group will undertake 6 weeks of exercise, twice a week, by watching videotaped sessions and once a week attend an informative behavioural video session on how to manage pain.
Group 2: This group will follow specified, mapped green journeys by walking twice a week.
Group 3 (control): This group will receive a booklet with examples of exercise and information on how to manage pain and encouragement to increase physical activity.
Randomisation is done via a computer-generated excel file. The interventions will last for 6 weeks, and we will assess patients at baseline, 6 weeks and 3 months.
Primary outcome measure
Self-reported functionality measured by KOOS at baseline, 6 weeks and 3 months
Secondary outcome measures
Functionality measured by Timed Up and Go Test at baseline, 6 weeks and 3 months
Overall trial start date
Overall trial end date
Reason abandoned (if study stopped)
Participant inclusion criteria
Citizens of the municipalities of West Attica in Athens, aged between 45 and 75 with knee osteoarthritis
Target number of participants
Participant exclusion criteria
Participants with musculoskeletal injury or surgery in the lower limbs, participants with cardiovascular problems, particpants with neurological disorders.
Recruitment start date
Recruitment end date
Countries of recruitment
Trial participating centre
Municipalities of West Attica, Peristeri and Egaleo
Kep Ygeias Peristeriou Paraskeuopoulou 23 Peristeri
Trial participating centre
University of West Attica
Agiou Spyridonos 28 Egaelo
State Scholarship Foundation (IKY)
Funding Body Type
Funding Body Subtype
Results and Publications
Publication and dissemination plan
1. Planned publication in a high-impact peer-reviewed journal.
2. Participants desiring to know the outcomes of the study will be informed by email.
IPD sharing statement:
The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request
Intention to publish date
Participant level data
Available on request
Basic results (scientific)