Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
MED
Study information
Scientific title
Acronym
Study hypothesis
Not provided at time of registration
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Not Specified
Patient information sheet
Not available in web format, please use the contact details below to request a patient information sheet
Condition
Mesothelioma
Intervention
1. Best supportive care + chemotherapy at presentation versus
2. Best supportive care + chemotherapy when symptoms progress
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measures
Not provided at time of registration
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/08/1999
Overall trial end date
31/12/2003
Reason abandoned
Eligibility
Participant inclusion criteria
1. Patients with histologically verified malignant mesothelioma - Performance status (PS) 0-2 - Asymptomatic or stable symptoms
2. Age at least 18 years
Participant type
Patient
Age group
Adult
Gender
Not Specified
Target number of participants
43
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
01/08/1999
Recruitment end date
31/12/2003
Locations
Countries of recruitment
United Kingdom
Trial participating centre
UKCCCR Register Co-ordinator
London
NW1 2DA
United Kingdom
Funders
Funder type
Research organisation
Funder name
Royal Marsden Hospital (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
2006 results on http://www.ncbi.nlm.nih.gov/pubmed/16317014
Publication citations
-
Results
O'Brien ME, Watkins D, Ryan C, Priest K, Corbishley C, Norton A, Ashley S, Rowell N, Sayer R, A randomised trial in malignant mesothelioma (M) of early (E) versus delayed (D) chemotherapy in symptomatically stable patients: the MED trial., Ann. Oncol., 2006, 17, 2, 270-275, doi: 10.1093/annonc/mdj073.