Contact information
Type
Scientific
Primary contact
Dr Dieter Melchart
ORCID ID
Contact details
Centre for Complementary Medicine Research
Department of Internal Medicine II
Technische Universität München
Munich
80801
Germany
+49 (0)89 726697 11
Dieter.Melchart@lrz.tu-muenchen.de
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N/A
Study information
Scientific title
Acronym
PEP-COMP
Study hypothesis
Not provided at time of registration
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Treatment
Patient information sheet
Condition
Migraine
Intervention
Individualised acupuncture (up to 15 sessions) or 100 to 200 mg metoprolol
Intervention type
Drug
Phase
Not Specified
Drug names
Metoprolol
Primary outcome measure
Not provided at time of registration
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/10/2002
Overall trial end date
31/01/2005
Reason abandoned (if study stopped)
Eligibility
Participant inclusion criteria
Adult patients with migraine fulfilling the criteria of the International Headache Society
(planned number of participants was 480; recruitment had to be terminated early, in summer 2004, due to recruitment problems and time limits of the project after recruiting 115 patients)
Participant type
Patient
Age group
Adult
Gender
Both
Target number of participants
115
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
01/10/2002
Recruitment end date
31/01/2005
Locations
Countries of recruitment
Germany
Trial participating centre
Centre for Complementary Medicine Research
Munich
80801
Germany
Sponsor information
Organisation
Munich Technical University - Centre for Complementary Medicine Research (Germany)
Sponsor details
Department of Internal Medicine II
Technische Universität München
Munich
80801
Germany
+49 (0)89 726697 11
Dieter.Melchart@lrz.tu-muenchen.de
Sponsor type
University/education
Website
Funders
Funder type
Other
Funder name
The study is funded by a group of 10 German statutory sickness funds (Germany)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Basic results (scientific)
Publication list
2006 results in http://www.ncbi.nlm.nih.gov/pubmed/17115982
Publication citations
-
Results
Streng A, Linde K, Hoppe A, Pfaffenrath V, Hammes M, Wagenpfeil S, Weidenhammer W, Melchart D, Effectiveness and tolerability of acupuncture compared with metoprolol in migraine prophylaxis., Headache, 46, 10, 1492-1502, doi: 10.1111/j.1526-4610.2006.00598.x.