Adjunctive benefits of systemic antibiotics to non-surgical treatment of generalised aggressive (early onset) periodontitis: a pilot study investigating treatment outcomes and prevalence and persistence of antibiotic resistance.
| ISRCTN | ISRCTN19566213 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN19566213 |
| Secondary identifying numbers | N0263128690 |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 29/07/2013
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Oral Health
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr G S Griffiths
Scientific
Scientific
Periodontology
Periodontology Department
Eastman Dental Institute
256 Gray's Inn Road
London
WC1X 8LD
United Kingdom
| Phone | +44 (0)20 7 915 1074 |
|---|
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Other |
| Study type | Treatment |
| Scientific title | |
| Study objectives | Does the use of systemic antibiotics have an adjunctive effect over mechanical cleaning and does it lead to an increase in antibiotics resistance? |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Periodontology; periodontitis |
| Intervention | Patients with periodontitis undergoing mechanical cleaning will be randomised to receive 1. Antibiotic 2.. Placebo |
| Intervention type | Other |
| Primary outcome measure | Changes in bleeding on probing, probeable crevice depth and lifetime attachment loss. |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/04/2003 |
| Completion date | 01/07/2004 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Both |
| Target number of participants | 40 |
| Key inclusion criteria | 40 patients from Periodontology |
| Key exclusion criteria | Does not match inclusion criteria |
| Date of first enrolment | 01/04/2003 |
| Date of final enrolment | 01/07/2004 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
Periodontology
London
WC1X 8LD
United Kingdom
WC1X 8LD
United Kingdom
Sponsor information
Department of Health
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Website | http://www.dh.gov.uk/Home/fs/en |
|---|
Funders
Funder type
Hospital/treatment centre
University College London Hospitals NHS Trust (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/10/2005 | Yes | No |
