Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N0192107577
Study information
Scientific title
Acronym
Study hypothesis
Does expiratory muscle training in motor neurone disease:
1. Increase expiratory muscle strength?
2. Improve cough efficacy?
3. Have any beneficial effect on survival?
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Treatment
Patient information sheet
Condition
Motor neurone disease (MND)
Intervention
Randomised controlled trial.
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measure
Vital capacity <50% predicted, onset of respiratory failure (PaCO2 >6), death.
Secondary outcome measures
Not provided at time of registration
Overall trial start date
12/02/2002
Overall trial end date
13/06/2003
Reason abandoned (if study stopped)
Eligibility
Participant inclusion criteria
Total number of subjects = 24.
Participant type
Patient
Age group
Not Specified
Gender
Not Specified
Target number of participants
24
Participant exclusion criteria
Does not match inclusion criteria
Recruitment start date
12/02/2002
Recruitment end date
13/06/2003
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Department of Medicine
Nottingham
NG7 2UH
United Kingdom
Sponsor information
Organisation
Department of Health (UK)
Sponsor details
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
Sponsor type
Government
Website
Funders
Funder type
Hospital/treatment centre
Funder name
Queens Medical Centre University Hospital NHS Trust (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Basic results (scientific)
Publication list