Randomised, controlled trial of N-acetylcysteine for treatment of acute exacerbations of chronic obstructive pulmonary disease.
| ISRCTN | ISRCTN21676344 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN21676344 |
| Secondary identifying numbers | N/A |
- Submission date
- 29/11/2004
- Registration date
- 30/11/2004
- Last edited
- 03/08/2007
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Respiratory
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Peter Black
Scientific
Scientific
Department of Medicine
University of Auckland
Private Bag 92019
Auckland
1001
New Zealand
| Phone | +64 93737599 ext 89797 |
|---|---|
| pn.black@auckland.ac.nz |
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Treatment |
| Scientific title | |
| Study objectives | Not provided at time of registration |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Chronic obstructive pulmonary disease |
| Intervention | N-acetylcysteine 600 mg twice daily or matching placebo. All participants received standard care including oxygen, nebulised salbutamol, oral prednisone and antibiotics (if indicated). |
| Intervention type | Other |
| Primary outcome measure | Not provided at time of registration |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/06/2001 |
| Completion date | 01/10/2001 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target number of participants | 50 |
| Key inclusion criteria | Patients admitted to hospital with an acute exacerbation of chronic obstructive pulmonary disease. |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/06/2001 |
| Date of final enrolment | 01/10/2001 |
Locations
Countries of recruitment
- New Zealand
Study participating centre
Department of Medicine
Auckland
1001
New Zealand
1001
New Zealand
Sponsor information
Health Research Council of New Zealand
Government
Government
PO Box 5541
Wellesley St
Auckland
1001
New Zealand
| Phone | +64 93035200 |
|---|---|
| info@hrc.govt.nz | |
| Website | http://www.hrc.govt.nz/ |
"ROR" |
https://ror.org/00zbf3d93 |
Funders
Funder type
Government
Health Research Council of New Zealand (ref: HRC 01/206)
Government organisation / National government
Government organisation / National government
- Alternative name(s)
- HRCNewZealand, HRC New Zealand, HRC
- Location
- New Zealand
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | Results | 06/12/2004 | Yes | No |
