Assessment of the lipid lowering agents on plasma homocysteine concentration and renal function
| ISRCTN | ISRCTN22151635 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN22151635 |
| Secondary identifying numbers | N0211136321 |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 17/04/2015
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Brian Starkey
Scientific
Scientific
Royal Surrey County Hospital Trust
Egerton Road
Guildford
GU2 5XX
United Kingdom
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Treatment |
| Scientific title | Assessment of the lipid lowering agents on plasma homocysteine concentration and renal function |
| Study objectives | Are the benefits of fibrate therapy offset by an increase in plasma homocysteine? |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Cardiovascular: Hyperlipidemia |
| Intervention | 3 groups: 1. Group 1 = Fibrate 1 2. Group 2 = Fibrate 2 3. Group 3 = Statin (Control) |
| Intervention type | Drug |
| Pharmaceutical study type(s) | |
| Phase | Not Applicable |
| Drug / device / biological / vaccine name(s) | Lipid lowering agents |
| Primary outcome measure | Measurements of renal function, plasma homocysteine and lipids over an 8-month period |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/11/2003 |
| Completion date | 30/09/2005 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Both |
| Target number of participants | 60 |
| Key inclusion criteria | Adult patients attending the lipid clinic with raised cholesterol and triglycerides |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/11/2003 |
| Date of final enrolment | 30/09/2005 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
Royal Surrey County Hospital Trust
Guildford
GU2 5XX
United Kingdom
GU2 5XX
United Kingdom
Sponsor information
Department of Health
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Website | http://www.dh.gov.uk/Home/fs/en |
|---|
Funders
Funder type
Government
Royal Surrey County Hospital NHS Trust (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
