Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N0192080686
Study information
Scientific title
A randomised double blind placebo controlled trial of the addition of metformin to optimal treatment in patients with chronic heart failure. Assessment by regional haemodynamics neurohumoral activation and symptomatic well being
Acronym
Study hypothesis
To determine whether metformin is of benefit in the treatment of patients with congestive heart failure.
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Treatment
Patient information sheet
Not available in web format, please use the contact details below to request a patient information sheet
Condition
Cardiovascular: Congestive heart failure (CHF)
Intervention
Randomised controlled trial.
Intervention type
Drug
Phase
Not Applicable
Drug names
Metformin
Primary outcome measures
1. Regional haemodynamics
2. Neurohumoral
3. Symptomatic well being
Secondary outcome measures
Not provided at time of registration
Overall trial start date
15/02/2000
Overall trial end date
31/08/2004
Reason abandoned
Eligibility
Participant inclusion criteria
Total number of subjects = 20
Participant type
Patient
Age group
Not Specified
Gender
Not Specified
Target number of participants
20
Participant exclusion criteria
Does not match inclusion criteria
Recruitment start date
15/02/2000
Recruitment end date
31/08/2004
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Nottingham University Hospitals NHS Trust
Nottingham
NG7 2UH
United Kingdom
Sponsor information
Organisation
Department of Health (UK)
Sponsor details
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
Sponsor type
Government
Website
Funders
Funder type
Hospital/treatment centre
Funder name
Nottingham University Hospitals NHS Trust (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary