Condition category
Circulatory System
Date applied
12/09/2003
Date assigned
12/09/2003
Last edited
27/10/2015
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr AJ Cowley

ORCID ID

Contact details

Department of Cardiovascular Medicine
D Floor South Block
Nottingham
NG7 2UH
United Kingdom

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N0192080686

Study information

Scientific title

A randomised double blind placebo controlled trial of the addition of metformin to optimal treatment in patients with chronic heart failure. Assessment by regional haemodynamics neurohumoral activation and symptomatic well being

Acronym

Study hypothesis

To determine whether metformin is of benefit in the treatment of patients with congestive heart failure.

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Treatment

Patient information sheet

Not available in web format, please use the contact details below to request a patient information sheet

Condition

Cardiovascular: Congestive heart failure (CHF)

Intervention

Randomised controlled trial.

Intervention type

Drug

Phase

Not Applicable

Drug names

Metformin

Primary outcome measures

1. Regional haemodynamics
2. Neurohumoral
3. Symptomatic well being

Secondary outcome measures

Not provided at time of registration

Overall trial start date

15/02/2000

Overall trial end date

31/08/2004

Reason abandoned

Eligibility

Participant inclusion criteria

Total number of subjects = 20

Participant type

Patient

Age group

Not Specified

Gender

Not Specified

Target number of participants

20

Participant exclusion criteria

Does not match inclusion criteria

Recruitment start date

15/02/2000

Recruitment end date

31/08/2004

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Nottingham University Hospitals NHS Trust
Nottingham
NG7 2UH
United Kingdom

Sponsor information

Organisation

Department of Health (UK)

Sponsor details

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Sponsor type

Government

Website

http://www.doh.gov.uk

Funders

Funder type

Hospital/treatment centre

Funder name

Nottingham University Hospitals NHS Trust (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Publication citations

Additional files

Editorial Notes