Contact information
Type
Scientific
Primary contact
Professor Ian Jacobs
ORCID ID
Contact details
Department of Emergency Medicine
University of Western Australia
35 Stirling Hwy
Nedlands
6009
Australia
+61 8 9346 4354
ijacobs@cyllene.uwa.edu.au
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
RA/4/1/0524
Study information
Scientific title
Acronym
Study hypothesis
Intravenous adrenaline administered intravenously does not improve survival
following outside of hospital cardiac arrest.
Ethics approval
Not provided at time of registration.
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Treatment
Patient information sheet
Condition
Cardiac Arrest
Intervention
Patients meeting the above criteria were randomised to receive either placebo administered intravenously (Control arm) or intravenous adrenaline according to standard resuscitation treatment guidelines (Experimental arm).
Intervention type
Drug
Phase
Not Specified
Drug names
adrenaline
Primary outcome measures
Survival to hospital discharge
Secondary outcome measures
1. Return of spontaneous circulation
2. Survival at one year
Overall trial start date
01/01/2005
Overall trial end date
30/06/2007
Reason abandoned
Eligibility
Participant inclusion criteria
All patients in cardiac arrest upon arrival of Ambulance Paramedics in whom resuscitation is initiated
Participant type
Patient
Age group
Adult
Gender
Both
Target number of participants
2250
Participant exclusion criteria
1. Patients under the age of 18 years
2. Patients in which advanced life support was not commenced (i.e. deceased
before ambulance arrival)
Recruitment start date
01/01/2005
Recruitment end date
30/06/2007
Locations
Countries of recruitment
Australia
Trial participating centre
Department of Emergency Medicine
Nedlands
6009
Australia
Sponsor information
Organisation
Western Australian Prehospital Care Research Unit (Australia)
Sponsor details
Department of Emergency Medicine
University of Western Australia
Nedlands
6009
Australia
Sponsor type
Hospital/treatment centre
Website
Funders
Funder type
Hospital/treatment centre
Funder name
National Health & Medical Research Council (Australia)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary