Condition category
Circulatory System
Date applied
27/03/2003
Date assigned
27/03/2003
Last edited
10/09/2007
Prospective/Retrospective
Prospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Professor Ian Jacobs

ORCID ID

Contact details

Department of Emergency Medicine
University of Western Australia
35 Stirling Hwy
Nedlands
6009
Australia
+61 8 9346 4354
ijacobs@cyllene.uwa.edu.au

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

RA/4/1/0524

Study information

Scientific title

Acronym

Study hypothesis

Intravenous adrenaline administered intravenously does not improve survival
following outside of hospital cardiac arrest.

Ethics approval

Not provided at time of registration.

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Treatment

Patient information sheet

Condition

Cardiac Arrest

Intervention

Patients meeting the above criteria were randomised to receive either placebo administered intravenously (Control arm) or intravenous adrenaline according to standard resuscitation treatment guidelines (Experimental arm).

Intervention type

Drug

Phase

Not Specified

Drug names

adrenaline

Primary outcome measures

Survival to hospital discharge

Secondary outcome measures

1. Return of spontaneous circulation
2. Survival at one year

Overall trial start date

01/01/2005

Overall trial end date

30/06/2007

Reason abandoned

Eligibility

Participant inclusion criteria

All patients in cardiac arrest upon arrival of Ambulance Paramedics in whom resuscitation is initiated

Participant type

Patient

Age group

Adult

Gender

Both

Target number of participants

2250

Participant exclusion criteria

1. Patients under the age of 18 years
2. Patients in which advanced life support was not commenced (i.e. deceased
before ambulance arrival)

Recruitment start date

01/01/2005

Recruitment end date

30/06/2007

Locations

Countries of recruitment

Australia

Trial participating centre

Department of Emergency Medicine
Nedlands
6009
Australia

Sponsor information

Organisation

Western Australian Prehospital Care Research Unit (Australia)

Sponsor details

Department of Emergency Medicine
University of Western Australia
Nedlands
6009
Australia

Sponsor type

Hospital/treatment centre

Website

http://www.uwa.edu.au/

Funders

Funder type

Hospital/treatment centre

Funder name

National Health & Medical Research Council (Australia)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Publication citations

Additional files

Editorial Notes