Contact information
Type
Scientific
Primary contact
Professor James V Parle
ORCID ID
Contact details
Department of Primary Care and General Practice
University of Birmingham
Edgbaston
B15 2TT
United Kingdom
+44 (0)121 414 6420
j.v.parle@bham.ac.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
226/657
Study information
Scientific title
Acronym
BETS (Birmingham Elderly Thyroid Study)
Study hypothesis
Not provided at time of registration
Ethics approval
Not provided at time of registration
Study design
Community based survey and randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
GP practices
Trial type
Screening
Patient information sheet
Condition
Thyroid dysfunction
Intervention
Intervention: Thyroxine replacement therapy. Dose to be increased by 25 mcg steps during 6 monthly period of monthly monitoring of thyroid function
Control: As for intervention group but placebo
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measures
Not provided at time of registration
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/01/2005
Overall trial end date
01/01/2006
Reason abandoned
Eligibility
Participant inclusion criteria
Phase 1: Aged 65+
Phase 2a: Patients identified in Phase 1 to be suffering from sub-clinical hyperthyroidism
Phase 2b: Patients identified in Phase 1 to be suffering from sub-clinical hypothyroidism
Participant type
Patient
Age group
Not Specified
Gender
Not Specified
Target number of participants
Not provided at time of registration
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
01/01/2005
Recruitment end date
01/01/2006
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Department of Primary Care and General Practice
Edgbaston
B15 2TT
United Kingdom
Sponsor information
Organisation
The Health Foundation (UK)
Sponsor details
90 Long Acre
London
WC2E 9RA
United Kingdom
+44 (0)20 7257 8000
info@health.org.uk
Sponsor type
Charity
Website
Funders
Funder type
Charity
Funder name
The Health Foundation (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
Results for community based survey: http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=17003083
Publication citations
-
Results for community based survey
Wilson S, Parle JV, Roberts LM, Roalfe AK, Hobbs FD, Clark P, Sheppard MC, Gammage MD, Pattison HM, Franklyn JA, , Prevalence of subclinical thyroid dysfunction and its relation to socioeconomic deprivation in the elderly: a community-based cross-sectional survey., J. Clin. Endocrinol. Metab., 2006, 91, 12, 4809-4816, doi: 10.1210/jc.2006-1557.