Nasal decongestant study: a prospective double-blind randomised comparative study of nasal decongestant and vasoconstrictive efficacy of two commonly used preparations, namely cocaine and adrenaline, with normal saline and adrenaline with normal saline

ISRCTN	ISRCTN24006995
DOI	https://doi.org/10.1186/ISRCTN24006995
Secondary identifying numbers	N0247184156

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Mr Deepak Gupta
Scientific

Swindon & Marlborough NHS Trust
The Great Western Hospital
Marlborough Road
Swindon
SN3 6BB
United Kingdom

Study design	Randomised controlled trial
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Hospital
Study type	Treatment
Scientific title
Study objectives	During endoscopic nasal surgery a pre-operative topical decongestion of the nose is achieved in the theatre by instillation of a decongestant solution. During operation this solution is used to achieve haemostasis. This research aims to compare the efficacy of two preparations and justify the use of cocaine.
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Surgery: Nose
Intervention	Cocaine and adrenaline with normal saline and adrenaline with normal saline
Intervention type	Drug
Pharmaceutical study type(s)
Phase	Not Specified
Drug / device / biological / vaccine name(s)	Cocaine, adrenaline, normal saline
Primary outcome measure	Not provided at time of registration
Secondary outcome measures	Not provided at time of registration
Overall study start date	01/08/2006
Completion date	01/11/2006

Participant type(s)	Patient
Age group	Not Specified
Sex	Not Specified
Target number of participants	Not provided at time of registration
Key inclusion criteria	Not provided at time of registration
Key exclusion criteria	Not provided at time of registration
Date of first enrolment	01/08/2006
Date of final enrolment	01/11/2006

Swindon & Marlborough NHS Trust

Swindon
SN3 6BB
United Kingdom

Record Provided by the NHSTCT Register - 2007 Update - Department of Health
Government

The Department of Health, Richmond House, 79 Whitehall
London
SW1A 2NL
United Kingdom

Government

Swindon and Marlborough NHS Trust (UK)

No information available

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan