Nocturnal nasal postive pressure ventilation plus oxygen therapy versus oxygen alone in severe stable chronic obstructive pulmonary disease
| ISRCTN | ISRCTN24818612 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN24818612 |
| Secondary identifying numbers | 921019 |
- Submission date
- 10/10/2002
- Registration date
- 10/10/2002
- Last edited
- 01/07/2009
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Respiratory
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr DSC Hui
Scientific
Scientific
Department of Medicine & Therapeutics
Prince of Wales Hospital
Chinese University of Hong Kong
-
-
Hong Kong
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Not specified |
| Study type | Not Specified |
| Scientific title | |
| Study objectives | Not provided at time of registration |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Respiratory diseases |
| Intervention | Patients will then be randomized into two groups receiving: 1. Non-invasive positive pressure ventilation (NPPV) plus LTOT, or 2. LTOT plus oral placebo over a 3-month period. NPPV will be delivered via a portable bilevel positive airway pressure (BiPAP) Duet device via a nasal or oral-nasal mask. |
| Intervention type | Drug |
| Pharmaceutical study type(s) | |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | oxygen |
| Primary outcome measure | Not provided at time of registration |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/01/2002 |
| Completion date | 31/12/2002 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target number of participants | Not provided at time of registration |
| Key inclusion criteria | Patients with severe stable chronic obstructive pulmonary disease with hypercapnic respiratory failure already on domiciliary long-term oxygen therapy (LTOT) |
| Key exclusion criteria | Does not meet inclusion criteria |
| Date of first enrolment | 01/01/2002 |
| Date of final enrolment | 31/12/2002 |
Locations
Countries of recruitment
- China
- Hong Kong
Study participating centre
Department of Medicine & Therapeutics
-
-
Hong Kong
-
Hong Kong
Sponsor information
Hong Kong Health Services Research Fund (Hong Kong)
Government
Government
Health Welfare and Food Bureau
Government Secretariat, HKSAR
20th floor Murray Building
Garden Road
-
-
Hong Kong
| Phone | +852 (0)2973 8288 |
|---|---|
| hsrf@hwfb.gov.hk | |
| Website | http://www.fhb.gov.hk/grants/english/funds/funds_hhsrf/funds_hhsrf_abt/funds_hhsrf_abt.html |
"ROR" |
https://ror.org/03qh32912 |
Funders
Funder type
Government
Hong Kong Health Services Research Fund (Hong Kong)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
