A randomised, double-blind, negatively-controlled study to determine whether the use of creams or ointments could alter the sensitivity of the skin to ultraviolet light during photo-therapy with narrow band UVB

ISRCTN	ISRCTN25782645
DOI	https://doi.org/10.1186/ISRCTN25782645
Secondary identifying numbers	N0547127254

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Dr Eunice Tan
Scientific

Department of Dermatology
Norfolk and Norwich University Hospital NHS Trust
Colney Lane
Norwich
NR4 7UY
United Kingdom

Study design	Randomised, double-blind, negatively-controlled study
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Not specified
Study type	Not Specified
Scientific title
Study objectives	Do creams or ointments applied before irradiation of the skin with narrow band UVB impair or improve the transmission of ultraviolet radiation to the skin?
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Not Applicable: Phototherapy
Intervention	Creams or ointments applied before irradiation vs standard practice
Intervention type	Other
Primary outcome measure	Determination of MED in each subject for each topical agent at 24 hours after narrow band UVB exposure.
Secondary outcome measures	Adverse events: pain, blistering, hyperpigmentary changes.
Overall study start date	03/03/2003
Completion date	31/05/2006

Participant type(s)	Patient
Age group	Not Specified
Sex	Not Specified
Target number of participants	20 patients
Key inclusion criteria	Not provided at time of registration
Key exclusion criteria	Not provided at time of registration
Date of first enrolment	03/03/2003
Date of final enrolment	31/05/2006

Department of Dermatology

Norwich
NR4 7UY
United Kingdom

Department of Health
Government

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Website	http://www.dh.gov.uk/Home/fs/en

Government

East Norfolk and Waveney Research Consortium - Norfolk and Norwich University Hospital/Norwich PCT (UK)

No information available

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	01/02/2011		Yes	No