Condition category
Signs and Symptoms
Date applied
14/07/2005
Date assigned
19/08/2005
Last edited
21/10/2015
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Prof Andreas Stuck

ORCID ID

Contact details

University Department of Geriatrics
Spital Bern - Ziegler
Morillonstrasse 75-91
Berne
CH-3001
Switzerland
+41 (0)31 970 73 29
andreas.stuck@spitalbern.ch

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

QLK6-CT-1999-02205

Study information

Scientific title

Disability prevention in the older population: use of information technology for health risk appraisal and prevention of functional decline

Acronym

PRO-AGE (PRevention in Older People - Assessment in GEneralists' practices)

Study hypothesis

The goal of the project is to change health risk behaviours in older persons with the longer-term aim of preventing disability and minimising unnecessary service utilisation. This is achieved by the development of a new intervention that could be integrated into primary care at relatively low costs and that could be used as a cross-national database for comparative evaluation on determinants of healthy ageing.

We hypothesise that at each site the intervention will:
1. Result in favourable changes in health behaviour:
1.1. Higher level of physical activity
1.2. Reduced fat intake
1.3. Higher fruit/fibre intake
1.4. Reduction of hazardous alcohol use
1.5. Increase in seat belt use
1.6. Reduction of smoking
2. Result in a higher uptake of preventive care:
2.1. Colon cancer screening
2.2. Breast cancer screening
2.3. Influenza vaccination
2.4. Pneumococcal vaccination
2.5. Blood pressure measurement
2.6. Glucose measurement
2.7. Cholesterol measurement
2.8. Vision screening
2.9. Hearing screening
2.10. Dentist visits
3. Improve older persons’ self efficacy in patient-physician interaction and taking care of ones own health

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

GP practices

Trial type

Prevention

Patient information sheet

Condition

The Ageing Population and Disability/Epidemiology

Intervention

We conducted three randomised controlled studies (three sites: Hamburg, London, Bern). The intervention consisted of the administration of the health risk appraisal for older persons (HRA-O), and of a site specific reinforcement. In Hamburg, the reinforcement consisted of small group sessions or of home visits, in London of computer-based support and a computer-assisted reminder system, and in Bern of home visits.

Control: no intervention

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

1. Self-reported use of preventive care at one-year follow-up
2. Self-reported health behaviour at one-year follow-up

Secondary outcome measures

1. Self-reported health and functional parameters at one-year follow-up
2. Self-efficacy in patient-physician interaction

Overall trial start date

01/02/2000

Overall trial end date

31/01/2003

Reason abandoned

Eligibility

Participant inclusion criteria

In each site about 20 - 30 general physician practices (three in London) generate lists of all persons aged 65 and older (Germany: 60 and older) in their practices.

Participant type

Patient

Age group

Senior

Gender

Both

Target number of participants

10,000

Participant exclusion criteria

1. Cognitive impairment
2. Dependent in basic activities of daily living (BADL) or living in nursing home
3. Terminal disease
4. Did not speak national language

Recruitment start date

01/02/2000

Recruitment end date

31/01/2003

Locations

Countries of recruitment

Germany, Switzerland, United Kingdom

Trial participating centre

University Department of Geriatrics
Berne
CH-3001
Switzerland

Sponsor information

Organisation

University of Berne (Switzerland)

Sponsor details

Department of Geriatrics
Spital Berne - Ziegler
Morillonstrasse 75-91
Berne
CH-3001
Switzerland
+41 (0)31 970 73 29
andreas.stuck@spitalbern.ch

Sponsor type

University/education

Website

Funders

Funder type

Government

Funder name

European Union (Belgium) (ref: QLK6-CT-1999-02205)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

Federal Office of Education and Science (Switzerland) (ref: BBW 990311.1)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

The German Federal Ministry for Family, Senior Citizens, Women and Youth (Bundesministerium für Familie, Senioren, Frauen und Jugend) (Germany)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

Max und Ingeburg Herz Foundation (Max und Ingeburg Herz Stiftung) (Germany)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

Robert Bosch Foundation (Robert Bosch Stiftung) (Germany)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2015 results in http://www.ncbi.nlm.nih.gov/pubmed/26479077

Results in:
1. http://www.ncbi.nlm.nih.gov/pubmed/12446293 (feasibility of the self-administered questionnaire)
2. http://www.ncbi.nlm.nih.gov/pubmed/11866651 (systematic review and meta-regression analysis)
3. http://www.ncbi.nlm.nih.gov/pubmed/16913998 (validation of the brief self-administered questionnaire)
4. http://www.ncbi.nlm.nih.gov/pubmed/18031489 (development of the Geriatric Pain Measure short form)
5. http://www.ncbi.nlm.nih.gov/pubmed/18755784 (health risk appraisal)

Publication citations

  1. Stuck AE, Elkuch P, Dapp U, Anders J, Iliffe S, Swift CG, , Feasibility and yield of a self-administered questionnaire for health risk appraisal in older people in three European countries., Age Ageing, 2002, 31, 6, 463-467.

  2. Stuck AE, Egger M, Hammer A, Minder CE, Beck JC, Home visits to prevent nursing home admission and functional decline in elderly people: systematic review and meta-regression analysis., JAMA, 2002, 287, 8, 1022-1028.

  3. Wagner JT, Bachmann LM, Boult C, Harari D, von Renteln-Kruse W, Egger M, Beck JC, Stuck AE, Predicting the risk of hospital admission in older persons--validation of a brief self-administered questionnaire in three European countries., J Am Geriatr Soc, 2006, 54, 8, 1271-1276, doi: 10.1111/j.1532-5415.2006.00829.x.

  4. Blozik E, Stuck AE, Niemann S, Ferrell BA, Harari D, von Renteln-Kruse W, Gillmann G, Beck JC, Clough-Gorr KM, Geriatric Pain Measure short form: development and initial evaluation., J Am Geriatr Soc, 2007, 55, 12, 2045-2050, doi: 10.1111/j.1532-5415.2007.01474.x.

  5. Harari D, Iliffe S, Kharicha K, Egger M, Gillmann G, von Renteln-Kruse W, Beck J, Swift C, Stuck A, Promotion of health in older people: a randomised controlled trial of health risk appraisal in British general practice., Age Ageing, 2008, 37, 5, 565-571, doi: 10.1093/ageing/afn150.

Additional files

Editorial Notes

21/10/2015: Publication reference added.