Adjunctive Systemic and Locally Delivered Metronidazole in the Treatment of Periodontitis - A Controlled Clinical-Study

ISRCTN ISRCTN28883189
DOI https://doi.org/10.1186/ISRCTN28883189
Secondary identifying numbers N/A
Submission date
23/01/2004
Registration date
23/01/2004
Last edited
11/09/2013
Recruitment status
No longer recruiting
Overall study status
Completed
Condition category
Oral Health
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Prof RM Palmer
Scientific

UMDS
Div Primary Health Care
London
SE1 9RT
United Kingdom

Study information

Study designRandomised controlled trial
Primary study designInterventional
Secondary study designRandomised controlled trial
Study setting(s)Not specified
Study typeNot Specified
Scientific title
Study objectivesNot provided at time of registration
Ethics approval(s)Not provided at time of registration
Health condition(s) or problem(s) studiedOral health/stomatognathic diseases: Oral health/stomatognathic diseases
Intervention1. Subgingival scaling using ultrasonic scalers and local anaesthesia.
2. Subgingival scaling using ultrasonic scalers and local anaesthesia plus seven days of systemic metronidazole (200 mg tds).
3. Subgingival scaling using ultrasonic scalers and local anaesthesia plus two applications of 25% metronidazole gel one week apart in all sites with probing depths more than 4 mm.
Intervention typeDrug
Pharmaceutical study type(s)
PhaseNot Specified
Drug / device / biological / vaccine name(s)Metronidazole
Primary outcome measureNot provided at time of registration
Secondary outcome measuresNot provided at time of registration
Overall study start date01/01/1996
Completion date31/12/1997

Eligibility

Participant type(s)Patient
Age groupAdult
SexNot Specified
Target number of participants90
Key inclusion criteriaNot provided at time of registration
Key exclusion criteriaNot provided at time of registration
Date of first enrolment01/01/1996
Date of final enrolment31/12/1997

Locations

Countries of recruitment

  • England
  • United Kingdom

Study participating centre

UMDS
London
SE1 9RT
United Kingdom

Sponsor information

NHS R&D Regional Programme Register - Department of Health (UK)
Government

The Department of Health
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Phone +44 (0)20 7307 2622
Email dhmail@doh.gsi.org.uk
Website http://www.doh.gov.uk

Funders

Funder type

Government

NHS Executive London (UK)

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to shareNo
IPD sharing plan summaryNot provided at time of registration
Publication and dissemination planNot provided at time of registration
IPD sharing plan

Study outputs

Output type Details Date created Date added Peer reviewed? Patient-facing?
Results article results 13/06/1998 Yes No