Condition category
Circulatory System
Date applied
22/03/2004
Date assigned
15/04/2004
Last edited
11/02/2008
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Prof Friedhelm Beyersdorf

ORCID ID

Contact details

Department of Cardiovascular Surgery
University Hospital Freiburg
Hugstetterstr. 55
Freiburg
79106
Germany
+49 761 2702818
beyers@chir.ukl.uni-freiburg.de

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

S 991228

Study information

Scientific title

Acronym

CRAIL

Study hypothesis

Not provided at time of registration

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Not Specified

Patient information sheet

Condition

Acutely ischaemic limb

Intervention

Embolectomy/Thrombectomy vs controlled reperfusion after Embolectomy/Thrombectomy

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Not provided at time of registration

Secondary outcome measures

Not provided at time of registration

Overall trial start date

01/01/2004

Overall trial end date

31/12/2007

Reason abandoned

Eligibility

Participant inclusion criteria

1. Patient >18 years
2. Acute arterial occlusion of one or both lower limbs (Rutherford IIa-III)

Participant type

Patient

Age group

Adult

Gender

Not Specified

Target number of participants

Not provided at time of registration

Participant exclusion criteria

1. Patients having undergone an attempt at recanalisation (Lyse etc.)
2. Heart failure (New York Heart Association [NYHA] IV)
3. Terminal kidney failure
4. Patients with a known aneurysm of the arteria poplitea

Recruitment start date

01/01/2004

Recruitment end date

31/12/2007

Locations

Countries of recruitment

Germany

Trial participating centre

Department of Cardiovascular Surgery
Freiburg
79106
Germany

Sponsor information

Organisation

University Hospital Freiburg (Germany)

Sponsor details

Department of Cardiovascular Surgery
University Hospital Freiburg
Hugstetterstr.55
Freiburg
79106
Germany
+49 761 2702818
beyers@chir.ukl.uni-freiburg.de

Sponsor type

Hospital/treatment centre

Website

http://www.uni-freiburg.de/index_en.php

Funders

Funder type

Government

Funder name

Deutsche Forschungsgemeinschaft, Bonn, Germany

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

Dr. Köhler-Chemie, Alsbach-Hähnlein, Germany

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

Local research commission, University hospital Freiburg, Germany

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2005 preliminary study on http://www.ncbi.nlm.nih.gov/pubmed/16242556

Publication citations

  1. Preliminary study

    Wilhelm MP, Schlensak C, Hoh A, Knipping L, Mangold G, Dallmeier Rojas D, Beyersdorf F, Controlled reperfusion using a simplified perfusion system preserves function after acute and persistent limb ischemia: a preliminary study., J. Vasc. Surg., 2005, 42, 4, 690-694, doi: 10.1016/j.jvs.2005.05.055.

Additional files

Editorial Notes