The effects of fentanyl, alfentanil and remifentanil on the cardiovascular responses during rigid bronchoscopy
| ISRCTN | ISRCTN31439885 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN31439885 |
| Secondary identifying numbers | N0185146397 |
- Submission date
- 30/09/2005
- Registration date
- 30/09/2005
- Last edited
- 25/04/2014
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr S Dudnikov
Scientific
Scientific
Department of Anaesthesia
Derriford Hospital
Plymouth
PL6 8DH
United Kingdom
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Not specified |
| Study type | Not Specified |
| Scientific title | |
| Study objectives | We are planning to investigate the effects of fentanyl, alfentanil and remifentanil on the cardiovascular responses during rigid bronchoscopy. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Cardiovascular: |
| Intervention | Patients undergoing rigid bronchoscopy will be randomised into the three drug groups. Measurement of muscle relaxation, arterial blood pressure and heart rate. |
| Intervention type | Other |
| Primary outcome measure | Changes in arterial blood pressures and heart rate. |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 25/09/2003 |
| Completion date | 25/03/2004 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Not Specified |
| Target number of participants | 60 |
| Key inclusion criteria | 60 adults |
| Key exclusion criteria | 1. Untreated systemic hypertension with SABP>160mmHg and /or DABP> 105mm Hg 2. Arythmias and heart conduction defects 3. Severe bronchial asthma |
| Date of first enrolment | 25/09/2003 |
| Date of final enrolment | 25/03/2004 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
Department of Anaesthesia
Plymouth
PL6 8DH
United Kingdom
PL6 8DH
United Kingdom
Sponsor information
Department of Health
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Phone | +44 (0)20 7307 2622 |
|---|---|
| dhmail@doh.gsi.org.uk | |
| Website | http://www.dh.gov.uk/Home/fs/en |
Funders
Funder type
Government
Plymouth Hospitals NHS Trust (UK), NHS R&D Support Funding
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
