Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N0185146397
Study information
Scientific title
Acronym
Study hypothesis
We are planning to investigate the effects of fentanyl, alfentanil and remifentanil on the cardiovascular responses during rigid bronchoscopy.
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Not Specified
Patient information sheet
Condition
Cardiovascular:
Intervention
Patients undergoing rigid bronchoscopy will be randomised into the three drug groups. Measurement of muscle relaxation, arterial blood pressure and heart rate.
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measures
Changes in arterial blood pressures and heart rate.
Secondary outcome measures
Not provided at time of registration
Overall trial start date
25/09/2003
Overall trial end date
25/03/2004
Reason abandoned
Eligibility
Participant inclusion criteria
60 adults
Participant type
Patient
Age group
Adult
Gender
Not Specified
Target number of participants
60
Participant exclusion criteria
1. Untreated systemic hypertension with SABP>160mmHg and /or DABP> 105mm Hg
2. Arythmias and heart conduction defects
3. Severe bronchial asthma
Recruitment start date
25/09/2003
Recruitment end date
25/03/2004
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Department of Anaesthesia
Plymouth
PL6 8DH
United Kingdom
Sponsor information
Organisation
Department of Health
Sponsor details
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
+44 (0)20 7307 2622
dhmail@doh.gsi.org.uk
Sponsor type
Government
Website
Funders
Funder type
Government
Funder name
Plymouth Hospitals NHS Trust (UK), NHS R&D Support Funding
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary