Contact information
Type
Scientific
Primary contact
Prof Roger Jones
ORCID ID
Contact details
General Practice & Primary Care
Guys
Kings & St Thomas School of Medicine
5 Lambeth Walk
London
SE11 6SP
United Kingdom
+44 (0)207 735 8881/2
roger.jones@kcl.ac.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
PSI03-32
Study information
Scientific title
Acronym
Study hypothesis
To determine whether the use of a Helicobacter pylori 'test and treat' strategy in general practice was associated with any improvement in clinical outcome or resource utilisation.
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
GP practices
Trial type
Treatment
Patient information sheet
Condition
Peptic ulcer disease
Intervention
Randomised trial comparing a Helicobacter pylori test-and-treat strategy with referral to direct access endoscopy in the management of dyspepsia in general practice.
Intervention type
Drug
Phase
Not Applicable
Drug names
Helicobacter pylori
Primary outcome measure
1. Health care utilisation
2. Consulting rates
3. Prescribing rates
Secondary outcome measures
No secondary outcome measures
Overall trial start date
01/05/1995
Overall trial end date
01/09/1998
Reason abandoned (if study stopped)
Eligibility
Participant inclusion criteria
A control group of practices in south east London pursuing 'usual' management of Helicobacter pylori, including endoscopy compared with a study group in which a near-patient test kit for Helicobacter pylori was provided for use on all patients under the age of 45 with persistent dyspepsia.
Participant type
Patient
Age group
Adult
Gender
Both
Target number of participants
232
Participant exclusion criteria
Does not meet with inclusion criteria
Recruitment start date
01/05/1995
Recruitment end date
01/09/1998
Locations
Countries of recruitment
United Kingdom
Trial participating centre
General Practice & Primary Care
London
SE11 6SP
United Kingdom
Sponsor information
Organisation
Record Provided by the NHS R&D 'Time-Limited' National Programme Register - Department of Health (UK)
Sponsor details
The Department of Health
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
Sponsor type
Government
Website
Funders
Funder type
Government
Funder name
NHS Primary and Secondary Care Interface National Research and Development Programme (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Basic results (scientific)
Publication list
1999 results in http://www.ncbi.nlm.nih.gov/pubmed/10622066
Publication citations
-
Results
Jones R, Tait C, Sladen G, Weston-Baker J, A trial of a test-and-treat strategy for Helicobacter pylori positive dyspeptic patients in general practice., Int. J. Clin. Pract., 1999, 53, 6, 413-416.