Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
LU18
Study information
Scientific title
Endobronchial obstruction trial: a randomised controlled trial
Acronym
Study hypothesis
To compare endobronchial treatment versus external beam radiotherapy in the management of endotracheal or endobronchial obstruction by lung cancer
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Not Specified
Patient information sheet
Condition
Cancer
Intervention
1. One group receives endobronchial treatment
2. The other group receives external beam radiotherapy
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measures
1. Palliation
2. Quality of life
3. Survival time
4. Other
Secondary outcome measures
Not provided at time of registration
Overall trial start date
09/10/1993
Overall trial end date
01/01/1999
Reason abandoned
Lack of participants
Eligibility
Participant inclusion criteria
Partial obstruction of the trachea, partial or complete obstruction of a main bronchus
Participant type
Patient
Age group
Adult
Gender
Both
Target number of participants
400. Added 18/08/09: trial intake stopped in November 1996
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
09/10/1993
Recruitment end date
01/01/1999
Locations
Countries of recruitment
United Kingdom
Trial participating centre
MRC Clinical Trials Unit
London
NW1 2DA
United Kingdom
Sponsor information
Organisation
Medical Research Council (MRC) (UK)
Sponsor details
20 Park Crescent
London
W1B 1AL
United Kingdom
+44 (0)20 7636 5422
clinical.trial@headoffice.mrc.ac.uk
Sponsor type
Research council
Website
Funders
Funder type
Research council
Funder name
Medical Research Council (MRC) (UK)
Alternative name(s)
MRC
Funding Body Type
government organisation
Funding Body Subtype
Federal/National Government
Location
United Kingdom
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
1999 results in: https://www.ncbi.nlm.nih.gov/pubmed/10465472
Publication citations
-
Report
Moghissi K, Bond MG, Sambrook RJ, Stephens RJ, Hopwood P, Girling DJ, Treatment of endotracheal or endobronchial obstruction by non-small cell lung cancer: lack of patients in an MRC randomized trial leaves key questions unanswered. Medical Research Council Lung Cancer Working Party., Clin Oncol (R Coll Radiol), 1999, 11, 3, 179-183.