Condition category
Cancer
Date applied
28/02/2001
Date assigned
28/02/2001
Last edited
18/08/2009
Prospective/Retrospective
Retrospectively registered
Overall trial status
Stopped
Recruitment status
Stopped

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Danielle Andrews

ORCID ID

Contact details

MRC Clinical Trials Unit
222 Euston Road
London
NW1 2DA
United Kingdom

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

LU18

Study information

Scientific title

Acronym

Study hypothesis

To compare endobronchial treatment versus external beam radiotherapy in the management of endotracheal or endobronchial obstruction by lung cancer

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Not Specified

Patient information sheet

Condition

Cancer

Intervention

1. One group receives endobronchial treatment
2. The other group receives external beam radiotherapy

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

1. Palliation
2. Quality of life
3. Survival time
4. Other

Secondary outcome measures

Not provided at time of registration

Overall trial start date

09/10/1993

Overall trial end date

01/01/1999

Reason abandoned

Lack of participants

Eligibility

Participant inclusion criteria

Partial obstruction of the trachea, partial or complete obstruction of a main bronchus

Participant type

Patient

Age group

Not Specified

Gender

Not Specified

Target number of participants

400
Added 18/08/09: trial intake stopped in November 1996

Participant exclusion criteria

Not provided at time of registration

Recruitment start date

09/10/1993

Recruitment end date

01/01/1999

Locations

Countries of recruitment

United Kingdom

Trial participating centre

MRC Clinical Trials Unit
London
NW1 2DA
United Kingdom

Sponsor information

Organisation

Medical Research Council (MRC) (UK)

Sponsor details

20 Park Crescent
London
W1B 1AL
United Kingdom
+44 20 7636 5422
clinical.trial@headoffice.mrc.ac.uk

Sponsor type

Research council

Website

http://www.mrc.ac.uk

Funders

Funder type

Research council

Funder name

Medical Research Council (MRC) (UK)

Alternative name(s)

MRC

Funding Body Type

private sector organisation

Funding Body Subtype

other non-profit

Location

United Kingdom

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Report in http://www.ncbi.nlm.nih.gov/pubmed/10465472

Publication citations

  1. Report

    Moghissi K, Bond MG, Sambrook RJ, Stephens RJ, Hopwood P, Girling DJ, Treatment of endotracheal or endobronchial obstruction by non-small cell lung cancer: lack of patients in an MRC randomized trial leaves key questions unanswered. Medical Research Council Lung Cancer Working Party., Clin Oncol (R Coll Radiol), 1999, 11, 3, 179-183.

Additional files

Editorial Notes