Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
G9533930
Study information
Scientific title
Acronym
MASS
Study hypothesis
To assess the effect of ultrasound screening for abdominal aortic aneurysm (AAA) on mortality from ruptured AAA.
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Hospitals
Trial type
Screening
Patient information sheet
Condition
Cardiovascular
Intervention
Ultrasound screening/control
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measure
1. Mortality for ruptured AAA as detected through the ONS and overall mortality
2. Cost effectiveness of screening for AAA and its effect on quality of life
Secondary outcome measures
Not provided at time of registration
Overall trial start date
17/02/1997
Overall trial end date
16/02/2007
Reason abandoned (if study stopped)
Eligibility
Participant inclusion criteria
Men aged 65-74 years on GP lists
Participant type
Patient
Age group
Senior
Gender
Male
Target number of participants
66,000
Participant exclusion criteria
1. Died before randomisation
2. Incorrect patient demographics
Recruitment start date
17/02/1997
Recruitment end date
16/02/2007
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Scott Research Unit
Chichester
PO19 4SE
United Kingdom
Sponsor information
Organisation
Medical Research Council (MRC) (UK)
Sponsor details
20 Park Crescent
London
W1B 1AL
United Kingdom
+44 (0)20 7636 5422
clinical.trial@headoffice.mrc.ac.uk
Sponsor type
Research council
Website
Funders
Funder type
Research council
Funder name
Medical Research Council (MRC) (UK)
Alternative name(s)
MRC
Funding Body Type
government organisation
Funding Body Subtype
Federal/National Government
Location
United Kingdom
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Basic results (scientific)
Publication list
1. 2007 results in http://www.ncbi.nlm.nih.gov/pubmed/17502630
2. 2009 results in http://www.ncbi.nlm.nih.gov/pubmed/19553269
3. 2012 results in http://www.ncbi.nlm.nih.gov/pubmed/23034729
Publication citations
-
Results
Kim LG, P Scott RA, Ashton HA, Thompson SG, , A sustained mortality benefit from screening for abdominal aortic aneurysm., Ann. Intern. Med., 2007, 146, 10, 699-706.
-
Results
Thompson SG, Ashton HA, Gao L, Scott RA, , Screening men for abdominal aortic aneurysm: 10 year mortality and cost effectiveness results from the randomised Multicentre Aneurysm Screening Study., BMJ, 2009, 338, b2307.
-
Results
Thompson SG, Ashton HA, Gao L, Buxton MJ, Scott RA, , Final follow-up of the Multicentre Aneurysm Screening Study (MASS) randomized trial of abdominal aortic aneurysm screening., Br J Surg, 2012, 99, 12, 1649-1656, doi: 10.1002/bjs.8897.