Condition category
Circulatory System
Date applied
23/08/2000
Date assigned
23/08/2000
Last edited
18/08/2009
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr JD Skehan

ORCID ID

Contact details

Department of Cardiology
Glenfield NHS Trust
Groby Road
Leicester
LE3 9QP
United Kingdom

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

G9403190

Study information

Scientific title

Acronym

UKPACE

Study hypothesis

Prospective assessment of single vs dual chamber pacing in elderly patients with atrioventricular conduction block

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Not Specified

Patient information sheet

Condition

Atrioventricular conduction block

Intervention

Single vs dual chamber pacing in elderly patients

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Primary end point:
1. All cause mortality
2. Outcome measures
3. Quality of Life
4. Cardiovascular Events
5. Cost Utility

Secondary outcome measures

Not provided at time of registration

Overall trial start date

01/02/1996

Overall trial end date

31/03/2003

Reason abandoned

Eligibility

Participant inclusion criteria

1. Age greater than 70 years
2. Advanced atrioventricular (A-V) block

Participant type

Patient

Age group

Senior

Gender

Not Specified

Target number of participants

2000

Participant exclusion criteria

If survival expected to be less than 1 year or totally immobile or confused

Recruitment start date

01/02/1996

Recruitment end date

31/03/2003

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Department of Cardiology
Leicester
LE3 9QP
United Kingdom

Sponsor information

Organisation

Medical Research Council (MRC) (UK)

Sponsor details

20 Park Crescent
London
W1B 1AL
United Kingdom
+44 20 7636 5422
clinical.trial@headoffice.mrc.ac.uk

Sponsor type

Research council

Website

http://www.mrc.ac.uk

Funders

Funder type

Research council

Funder name

Medical Research Council (MRC) (UK)

Alternative name(s)

MRC

Funding Body Type

private sector organisation

Funding Body Subtype

other non-profit

Location

United Kingdom

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2005 results in http://www.ncbi.nlm.nih.gov/pubmed/16014884

Publication citations

  1. Results

    Toff WD, Camm AJ, Skehan JD, , Single-chamber versus dual-chamber pacing for high-grade atrioventricular block., N. Engl. J. Med., 2005, 353, 2, 145-155, doi: 10.1056/NEJMoa042283.

Additional files

Editorial Notes