Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
G9403190
Study information
Scientific title
Acronym
UKPACE
Study hypothesis
Prospective assessment of single vs dual chamber pacing in elderly patients with atrioventricular conduction block
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Not Specified
Patient information sheet
Condition
Atrioventricular conduction block
Intervention
Single vs dual chamber pacing in elderly patients
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measures
Primary end point:
1. All cause mortality
2. Outcome measures
3. Quality of Life
4. Cardiovascular Events
5. Cost Utility
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/02/1996
Overall trial end date
31/03/2003
Reason abandoned
Eligibility
Participant inclusion criteria
1. Age greater than 70 years
2. Advanced atrioventricular (A-V) block
Participant type
Patient
Age group
Senior
Gender
Not Specified
Target number of participants
2000
Participant exclusion criteria
If survival expected to be less than 1 year or totally immobile or confused
Recruitment start date
01/02/1996
Recruitment end date
31/03/2003
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Department of Cardiology
Leicester
LE3 9QP
United Kingdom
Sponsor information
Organisation
Medical Research Council (MRC) (UK)
Sponsor details
20 Park Crescent
London
W1B 1AL
United Kingdom
+44 (0)20 7636 5422
clinical.trial@headoffice.mrc.ac.uk
Sponsor type
Research council
Website
Funders
Funder type
Research council
Funder name
Medical Research Council (MRC) (UK)
Alternative name(s)
MRC
Funding Body Type
private sector organisation
Funding Body Subtype
other non-profit
Location
United Kingdom
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
2005 results in http://www.ncbi.nlm.nih.gov/pubmed/16014884
Publication citations
-
Results
Toff WD, Camm AJ, Skehan JD, , Single-chamber versus dual-chamber pacing for high-grade atrioventricular block., N. Engl. J. Med., 2005, 353, 2, 145-155, doi: 10.1056/NEJMoa042283.