Contact information
Type
Scientific
Primary contact
Mr Jeremy Wilkinson
ORCID ID
Contact details
Bone Metabolism Group
University of Sheffield
Division of Clinical Sciences
Northern General Hospital
Herries Road
Sheffield
S5 7AU
United Kingdom
+44 (0)114 271 4705
wilkomark@aol.com
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
W0597
Study information
Scientific title
Acronym
Study hypothesis
Not provided at time of registration
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Hospitals
Trial type
Treatment
Patient information sheet
Condition
Periprosthetic bone loss after total hip replacement
Intervention
Pamidronate sodium as a single 90 mg infusion versus saline infusion given on the 5th day postoperatively after total hip arthroplasty
Intervention type
Drug
Phase
Not Specified
Drug names
Pamidronate
Primary outcome measures
Not provided at time of registration
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/01/2002
Overall trial end date
01/01/2004
Reason abandoned
Eligibility
Participant inclusion criteria
Men and women undergoing primary total hip arthroplasty for osteoarthritis of the hip.
Participant type
Patient
Age group
Not Specified
Gender
Both
Target number of participants
Not provided at time of registration
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
01/01/2002
Recruitment end date
01/01/2004
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Bone Metabolism Group
Sheffield
S5 7AU
United Kingdom
Sponsor information
Organisation
Arthritis Research Campaign (ARC) (UK)
Sponsor details
Copeman House
St Mary's Court
St Mary's Gate
Chesterfield
Derbyshire
S41 7TD
United Kingdom
-
info@arc.org.uk
Sponsor type
Charity
Website
Funders
Funder type
Charity
Funder name
Arthritis Research Campaign (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
Results in http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=15607868
Publication citations
-
Results
Wilkinson JM, Eagleton AC, Stockley I, Peel NF, Hamer AJ, Eastell R, Effect of pamidronate on bone turnover and implant migration after total hip arthroplasty: a randomized trial., J. Orthop. Res., 2005, 23, 1, 1-8, doi: 10.1016/j.orthres.2004.06.004.