Condition category
Musculoskeletal Diseases
Date applied
06/01/2003
Date assigned
06/01/2003
Last edited
10/10/2007
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Mr Jeremy Wilkinson

ORCID ID

Contact details

Bone Metabolism Group
University of Sheffield
Division of Clinical Sciences
Northern General Hospital
Herries Road
Sheffield
S5 7AU
United Kingdom
+44 (0)114 271 4705
wilkomark@aol.com

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

W0597

Study information

Scientific title

Acronym

Study hypothesis

Not provided at time of registration

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Hospitals

Trial type

Treatment

Patient information sheet

Condition

Periprosthetic bone loss after total hip replacement

Intervention

Pamidronate sodium as a single 90 mg infusion versus saline infusion given on the 5th day postoperatively after total hip arthroplasty

Intervention type

Drug

Phase

Not Specified

Drug names

Pamidronate

Primary outcome measures

Not provided at time of registration

Secondary outcome measures

Not provided at time of registration

Overall trial start date

01/01/2002

Overall trial end date

01/01/2004

Reason abandoned

Eligibility

Participant inclusion criteria

Men and women undergoing primary total hip arthroplasty for osteoarthritis of the hip.

Participant type

Patient

Age group

Not Specified

Gender

Both

Target number of participants

Not provided at time of registration

Participant exclusion criteria

Not provided at time of registration

Recruitment start date

01/01/2002

Recruitment end date

01/01/2004

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Bone Metabolism Group
Sheffield
S5 7AU
United Kingdom

Sponsor information

Organisation

Arthritis Research Campaign (ARC) (UK)

Sponsor details

Copeman House
St Mary's Court
St Mary's Gate
Chesterfield
Derbyshire
S41 7TD
United Kingdom
-
info@arc.org.uk

Sponsor type

Charity

Website

http://www.arc.org.uk

Funders

Funder type

Charity

Funder name

Arthritis Research Campaign (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Results in http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=15607868

Publication citations

  1. Results

    Wilkinson JM, Eagleton AC, Stockley I, Peel NF, Hamer AJ, Eastell R, Effect of pamidronate on bone turnover and implant migration after total hip arthroplasty: a randomized trial., J. Orthop. Res., 2005, 23, 1, 1-8, doi: 10.1016/j.orthres.2004.06.004.

Additional files

Editorial Notes