Wean earlier and automatically with new technology: a multicentre, pilot randomised controlled study
| ISRCTN | ISRCTN43760151 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN43760151 |
| Secondary identifying numbers | N/A |
- Submission date
- 03/01/2006
- Registration date
- 30/01/2006
- Last edited
- 31/07/2013
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Respiratory
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Karen E. A. Burns
Scientific
Scientific
St Michael's Hospital
30 Bond street
3-075E Queen wing
Toronto
M5B 1W8
Canada
Study information
| Study design | Multicentre randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Not specified |
| Study type | Treatment |
| Scientific title | |
| Study acronym | The WEAN Study |
| Study objectives | The primary objective of this multicentre pilot study is to compare automatic and protocolised weaning and to evaluate compliance with the proposed weaning and sedation protocols |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Weaning intubated adults from invasive mechanical ventilation |
| Intervention | Automatic (computer-driven) weaning versus protocolized weaning |
| Intervention type | Other |
| Primary outcome measure | Compliance with the weaning and sedation protocols |
| Secondary outcome measures | 1. Acceptance of the weaning and sedation protocols 2. Weaning and Intensive Care Unit (ICU) related-complications 3. Time to successful completion of a Single Breath Test (SBT) and extubation |
| Overall study start date | 30/05/2006 |
| Completion date | 01/06/2006 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Both |
| Target number of participants | 90 |
| Key inclusion criteria | Patients who are invasively ventilated for at least 24 hours |
| Key exclusion criteria | 1. Age < 16 years 2. Tracheotomy 3. Pregnancy 4. Do not intubate (DNI) or do not resuscitate (DNR) patients 5. Planned extubation on the day of study inclusion 6. Planned surgery or procedures within 48 hours of randomization |
| Date of first enrolment | 30/05/2006 |
| Date of final enrolment | 01/06/2006 |
Locations
Countries of recruitment
- Canada
Study participating centre
St Michael's Hospital
Toronto
M5B 1W8
Canada
M5B 1W8
Canada
Sponsor information
Physician Services Incorporated (Canada)
Charity
Charity
5160 Yonge street
Suite 1006
Toronto
M2N 6L9
Canada
"ROR" |
https://ror.org/0385yzn06 |
|---|
Funders
Funder type
Charity
Physician Services Incorporated (Canada)
No information available
Draeger Canada (in kind)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Protocol article | protocol | 04/09/2009 | Yes | No | |
| Results article | results | 01/06/2013 | Yes | No |
