Non-cardiac chest pain: a randomised controlled trial of the effects of antidepressant and acid suppression treatment
| ISRCTN | ISRCTN44501456 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN44501456 |
| Secondary identifying numbers | N0123090782 |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 22/05/2017
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Signs and Symptoms
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Ms Nicola Turner
Scientific
Scientific
Research Office
Leicester General Hospital
Gwendolen Road
Leicester
LE5 4PW
United Kingdom
| Phone | +44 (0)116 258 4750/6318 |
|---|---|
| nicola.turner@uhl-tr.nhs.uk |
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Treatment |
| Scientific title | Non-cardiac chest pain: a randomised controlled trial of the effects of antidepressant and acid suppression treatment |
| Study objectives | 1. To investigate the efficacy of an antidepressant drug compared to acid blockade and placebo for symptomatic relief in non-cardiac chest pain 2. To collect data in an attempt to identify factors predicting response or non-response of these patients to this treatment 3. To develop treatment strategies for this difficult group of patients 4. To correlate effects of treatment with change pain perception and in psychiatric assessment 5. To investigate the effect of treatment on quality of life |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Non-cardiac chest pain |
| Intervention | Antidepressant drug compared to acid blockade and placebo |
| Intervention type | Drug |
| Pharmaceutical study type(s) | |
| Phase | Not Applicable |
| Drug / device / biological / vaccine name(s) | Antidepressant drug, acid blockade |
| Primary outcome measure | Not provided at time of registration |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/10/2000 |
| Completion date | 31/08/2003 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target number of participants | Not provided at time of registration |
| Key inclusion criteria | Patients with non-cardiac chest pain |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/10/2000 |
| Date of final enrolment | 31/08/2003 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
Research Office
Leicester
LE5 4PW
United Kingdom
LE5 4PW
United Kingdom
Sponsor information
Department of Health
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Website | http://www.dh.gov.uk/Home/fs/en |
|---|
Funders
Funder type
Government
University Hospitals of Leicester NHS Trust (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Editorial Notes
22/05/2017: No publications found in PubMed, verifying study status with principal investigator.
