Contact information
Type
Scientific
Primary contact
Dr David Kessler
ORCID ID
Contact details
Division of Primary Care
University of Bristol
Cotham House
Cotham Hill
Bristol
BS6 6JL
United Kingdom
david.kessler@bristol.ac.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N/A
Study information
Scientific title
Acronym
Study hypothesis
To evaluate the clinical and cost effectiveness of Internet based cognitive behavioural therapy (webCBT) for depression compared to a waiting list control in primary care. A qualitative study will be done as part of the trial to assess the acceptability of the intervention to patients and health care providers.
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Other
Trial type
Treatment
Patient information sheet
Condition
Depression
Intervention
Intervention: Up to eight one hour sessions of cognitive behavioural therapy (CBT) delivered online by a qualified psychologist.
Control: The control group will be on a waiting list for CBT of 8 months and will receive 'usual care' from their GP. This may include pharmacological treatment but will not include psychotherapy.
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measure
The Beck depression inventory score at 2 months adjusted for baseline.
Secondary outcome measures
EQ5D and SF-12 at 8 months
Overall trial start date
01/10/2005
Overall trial end date
30/09/2008
Reason abandoned (if study stopped)
Eligibility
Participant inclusion criteria
Patients with GP diagnosed depression in primary care. Diagnosis must be confirmed by standardised psychological measure.
Participant type
Patient
Age group
Not Specified
Gender
Not Specified
Target number of participants
470
Participant exclusion criteria
Does not match inclusion criteria
Recruitment start date
01/10/2005
Recruitment end date
30/09/2008
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Division of Primary Care
Bristol
BS6 6JL
United Kingdom
Sponsor information
Organisation
University of Bristol (UK)
Sponsor details
Gillian Tallents
Research Governance Manager
Research and Enterprise Development
Senate House
Tyndall Avenue
Bristol
BS8 1TH
United Kingdom
Gillian.Tallents@bristol.ac.uk
Sponsor type
University/education
Website
Funders
Funder type
Charity
Funder name
BUPA Foundation (UK) (ref: 683/G14)
Alternative name(s)
Funding Body Type
private sector organisation
Funding Body Subtype
Trusts, charities, foundations (both publically funded and privately funded)
Location
United Kingdom
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Basic results (scientific)
Publication list
2009 results in http://www.ncbi.nlm.nih.gov/pubmed/19700005
Publication citations
-
Results
Kessler D, Lewis G, Kaur S, Wiles N, King M, Weich S, Sharp DJ, Araya R, Hollinghurst S, Peters TJ, Therapist-delivered Internet psychotherapy for depression in primary care: a randomised controlled trial., Lancet, 2009, 374, 9690, 628-634, doi: 10.1016/S0140-6736(09)61257-5.