A randomised controlled trial of Internet based cognitive behavioural psychotherapy for depression

ISRCTN	ISRCTN45444578
DOI	https://doi.org/10.1186/ISRCTN45444578
Secondary identifying numbers	N/A

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Dr David Kessler
Scientific

Division of Primary Care
University of Bristol
Cotham House
Cotham Hill
Bristol
BS6 6JL
United Kingdom

Email	david.kessler@bristol.ac.uk

Study design	Randomised controlled trial
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Other
Study type	Treatment
Scientific title
Study objectives	To evaluate the clinical and cost effectiveness of Internet based cognitive behavioural therapy (webCBT) for depression compared to a waiting list control in primary care. A qualitative study will be done as part of the trial to assess the acceptability of the intervention to patients and health care providers.
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Depression
Intervention	Intervention: Up to eight one hour sessions of cognitive behavioural therapy (CBT) delivered online by a qualified psychologist. Control: The control group will be on a waiting list for CBT of 8 months and will receive 'usual care' from their GP. This may include pharmacological treatment but will not include psychotherapy.
Intervention type	Other
Primary outcome measure	The Beck depression inventory score at 2 months adjusted for baseline.
Secondary outcome measures	EQ5D and SF-12 at 8 months
Overall study start date	01/10/2005
Completion date	30/09/2008

Participant type(s)	Patient
Age group	Not Specified
Sex	Not Specified
Target number of participants	470
Key inclusion criteria	Patients with GP diagnosed depression in primary care. Diagnosis must be confirmed by standardised psychological measure.
Key exclusion criteria	Does not match inclusion criteria
Date of first enrolment	01/10/2005
Date of final enrolment	30/09/2008

Division of Primary Care

Bristol
BS6 6JL
United Kingdom

University of Bristol (UK)
University/education

Gillian Tallents
Research Governance Manager
Research and Enterprise Development
Senate House
Tyndall Avenue
Bristol
BS8 1TH
England
United Kingdom

Email	Gillian.Tallents@bristol.ac.uk
"ROR"	https://ror.org/0524sp257

Charity

BUPA Foundation (UK) (ref: 683/G14)
Private sector organisation / Trusts, charities, foundations (both public and private)

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	22/08/2009		Yes	No