Condition category
Urological and Genital Diseases
Date applied
02/11/2005
Date assigned
08/12/2005
Last edited
10/09/2009
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Simon Cheung

ORCID ID

Contact details

Department of Medicine
Queen Elizabeth Hospital
30 Gascoigne Road
Kowloon
-
Hong Kong
simoncycheung@gmail.com

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N/A

Study information

Scientific title

Acronym

Study hypothesis

To study whether tacrolimus is superior to cyclosporine in preserving renal function

Ethics approval

Yes, 1998

Study design

Prospective randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Hospitals

Trial type

Treatment

Patient information sheet

Condition

Cadaveric renal transplant

Intervention

Tacrolimus therapy or Neoral cyclosporine therapy

Intervention type

Drug

Phase

Not Specified

Drug names

Tacrolimus and cyclosporine

Primary outcome measures

Patient and graft survival, rejection rate

Secondary outcome measures

Course of renal function, cardiovascular risks, infection and malignancy

Overall trial start date

01/06/1998

Overall trial end date

31/12/2004

Reason abandoned

Eligibility

Participant inclusion criteria

Chinese patients receiving first cadaveric renal transplants consecutively between 01/06/98 and 31/12/04 in Queen Elizabeth Hospital in Hong Kong

Participant type

Patient

Age group

Adult

Gender

Both

Target number of participants

100

Participant exclusion criteria

Consent not available

Recruitment start date

01/06/1998

Recruitment end date

31/12/2004

Locations

Countries of recruitment

Hong Kong

Trial participating centre

Department of Medicine
Kowloon
-
Hong Kong

Sponsor information

Organisation

Queen Elizabeth Hospital (Hong Kong)

Sponsor details

30
Gascoigne Road
Kowloon
-
Hong Kong
simoncycheung@gmail.com

Sponsor type

Hospital/treatment centre

Website

Funders

Funder type

Hospital/treatment centre

Funder name

Queen Elizabeth Hospital (Hong Kong)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2006 results in http://www.ncbi.nlm.nih.gov/pubmed/16827683

Publication citations

  1. Results

    Cheung CY, Wong KM, Chan HW, Liu YL, Chan YH, Wong HS, Chak WL, Choi KS, Chau KF, Li CS, Paired kidney analysis of tacrolimus and cyclosporine microemulsion-based therapy in Chinese cadaveric renal transplant recipients., Transpl. Int., 2006, 19, 8, 657-666, doi: 10.1111/j.1432-2277.2006.00335.x.

Additional files

Editorial Notes