Decreased time on mechanical ventilation when comparing analgesia-based sedation using remifentanil versus standard hypnotic-based sedation for up to 10 days in intensive care unit patients: a randomised trial.

ISRCTN	ISRCTN47583497
DOI	https://doi.org/10.1186/ISRCTN47583497
Secondary identifying numbers	USA30226

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Dr Andrew Kirkham
Scientific

GlaxoSmithKline
Greenford Road
Greenford, Middlesex
UB6 OHE
United Kingdom

Study design	Randomised controlled trial
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Hospital
Study type	Treatment
Scientific title
Study objectives	Not provided at time of registration
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Medical or surgical patients requiring intensive care.
Intervention	Comparing analgesia-based sedation using remifentanil versus standard hypnotic-based sedation for up to 10 days in intensive care unit patients. Titration of analgesia/sedation to achieve optimal sedation. Regular assessments of haemodynamics.
Intervention type	Drug
Pharmaceutical study type(s)
Phase	Not Specified
Drug / device / biological / vaccine name(s)	Remifentanil
Primary outcome measure	Not provided at time of registration
Secondary outcome measures	Not provided at time of registration
Overall study start date	07/06/2002
Completion date	30/06/2003

Participant type(s)	Patient
Age group	Not Specified
Sex	Not Specified
Target number of participants	Not provided at time of registration
Key inclusion criteria	Critically ill patients requiring 3-10 days of mechanical ventilation.
Key exclusion criteria	Not provided at time of registration
Date of first enrolment	07/06/2002
Date of final enrolment	30/06/2003

GlaxoSmithKline

Greenford, Middlesex
UB6 OHE
United Kingdom

GlaxoSmithKline
Not defined

Greenford Road
Greenford
UB6 0HE
United Kingdom

"ROR"	https://ror.org/01xsqw823

Industry

GlaxoSmithKline (GSK)
Government organisation / For-profit companies (industry)

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	Results	01/06/2005		Yes	No