Randomised trial comparing 10% povidone-iodine with alcohol and 0.5% chlorhexidine with 70% alcohol for prevention of early infection associated with central venous catheter insertion

ISRCTN	ISRCTN51113796
DOI	https://doi.org/10.1186/ISRCTN51113796
Secondary identifying numbers	N0012175964

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Mrs PM Kleidon
Scientific

MRI 1 & 2
Great Ormond Street Hospital
Great Ormond Street
London
WC1N 3JH
United Kingdom

Study design	Randomised controlled trial
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Hospital
Study type	Prevention
Scientific title	Randomised trial comparing 10% povidone-iodine with alcohol and 0.5% chlorhexidine with 70% alcohol for prevention of early infection associated with central venous catheter insertion
Study objectives	To determine if one skin antiseptic is superior to others in prevention of insertion related central venous device infection.
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Surgery
Intervention	10% povidone-iodine with alcohol vs 0.5%chlorhexidine with 70% alcohol
Intervention type	Drug
Pharmaceutical study type(s)
Phase	Not Applicable
Drug / device / biological / vaccine name(s)	0% povidone-iodine with alcohol, and 0.5% chlorhexidine with 70% alcohol
Primary outcome measure	Not provided at time of registration
Secondary outcome measures	Not provided at time of registration
Overall study start date	31/01/2006
Completion date	30/01/2008

Participant type(s)	Patient
Age group	Child
Sex	Both
Target number of participants	500
Key inclusion criteria	Children requiring insertion of a central venous access device
Key exclusion criteria	Previous allergy to either skin preparations
Date of first enrolment	31/01/2006
Date of final enrolment	30/01/2008

Great Ormond Street Hospital

London
WC1N 3JH
United Kingdom

Record Provided by the NHSTCT Register - 2006 Update - Department of Health
Government

The Department of Health
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Government

Great Ormond Street Hospital for Children NHS Trust / Institute of Child Health (UK)

No information available

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan