Contact information
Type
Scientific
Primary contact
Dr David Thomas
ORCID ID
Contact details
Dept of Oral Surgery Medicine
University of Wales College of Medicine
Dental School
Heath Park
Cardiff
CF4 4XY
United Kingdom
+44 (0)1222 742442
ThomasDW2@cardiff.ac.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
RDO/90/17
Study information
Scientific title
Acronym
Study hypothesis
Rationalisation of antibiotic prescription for acute dental conditions in the primary care setting.
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
GP practices
Trial type
Not Specified
Patient information sheet
Condition
Oral health/stomatognathic diseases
Intervention
1. Development and piloting of the educational package
2. Training of academic detailer
3. Recruitment of the study population of general dental practitioners and general medical practitioners randomised into a test and a control group
4. Data collection and statistical analysis by questionnaires to collect patient and prescribing data at baseline for six months
5. Test group will receive patient and professionals-mediated educational materials and academic detailing visitation on prescribing antibiotics for dental conditions. The control group will continue with data collection as described in (4) above and will receive no additional intervention. Data collection will be maintained for both groups for at least 3 months.
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measure
1. Changes in the prescribing habits of general medical and general dental practitioners resulting in:
1.1 A reduction in the overall prescription of antibiotics.
1.2 A reduction in the unnecessary prescription of broad-spectrum antibiotics which contribute to the increase in
microbial resistance evident in the community.
1.3 Cost savings.
1.4 An indirect reduction of morbidity and mortality associated with anti-microbial resistant organisms.
2. A rationale for antibiotic prescribing
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/11/1998
Overall trial end date
31/03/2002
Reason abandoned (if study stopped)
Eligibility
Participant inclusion criteria
Not provided at time of registration
Participant type
Patient
Age group
Not Specified
Gender
Not Specified
Target number of participants
Not provided at time of registration
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
01/11/1998
Recruitment end date
31/03/2002
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Dept of Oral Surgery Medicine
Cardiff
CF4 4XY
United Kingdom
Sponsor information
Organisation
Record Provided by the NHS R&D 'Time-Limited' National Programme Register - Department of Health (UK)
Sponsor details
The Department of Health
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
Sponsor type
Government
Website
Funders
Funder type
Government
Funder name
NHS National Programme for Primary Dental Care (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Basic results (scientific)
Publication list
2006 results in http://www.ncbi.nlm.nih.gov/pubmed/16902573
Publication citations
-
Results
Seager JM, Howell-Jones RS, Dunstan FD, Lewis MA, Richmond S, Thomas DW, A randomised controlled trial of clinical outreach education to rationalise antibiotic prescribing for acute dental pain in the primary care setting., Br Dent J, 2006, 201, 4, 217-22; discussion 216, doi: 10.1038/sj.bdj.4813879.