The effect of probiotic therapy on nosocomial infections in the critically ill

ISRCTN ISRCTN51777318
DOI https://doi.org/10.1186/ISRCTN51777318
Secondary identifying numbers N0192133923
Submission date
30/09/2004
Registration date
30/09/2004
Last edited
18/10/2017
Recruitment status
No longer recruiting
Overall study status
Completed
Condition category
Infections and Infestations
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Contact information

Dr D Knight
Scientific

Department of Anaesthesia and Intensive Care
Queens Medical Centre
University Hospital
Nottingham
NG7 2UH
United Kingdom

Study information

Study designRandomised controlled trial
Primary study designInterventional
Secondary study designRandomised controlled trial
Study setting(s)Hospital
Study typePrevention
Participant information sheet Not available in web format, please use the contact details below to request a patient information sheet
Scientific titleThe effect of probiotic therapy on nosocomial infections in the critically ill
Study objectivesDoes early enteral feeding with probiotics reduce the rate of nosocomial (hospital acquired) infections in the critically ill?
Ethics approval(s)Not provided at time of registration
Health condition(s) or problem(s) studiedInfections and Infestations: Nosocomial infections
Intervention1. Lactobacillus
2. Placebo
Intervention typeDrug
Pharmaceutical study type(s)
PhaseNot Specified
Drug / device / biological / vaccine name(s)Probiotics
Primary outcome measureOropharyngeal nosocomial bacterial carriage rates, nosocomial infection rates, death rates, diarrhoea rates.
Secondary outcome measuresNot provided at time of registration
Overall study start date07/10/2003
Completion date31/12/2005

Eligibility

Participant type(s)Patient
Age groupNot Specified
SexBoth
Target number of participantsNot provided at time of registration
Key inclusion criteriaNot provided at time of registration
Key exclusion criteriaDoes not meet inclusion criteria
Date of first enrolment07/10/2003
Date of final enrolment31/12/2005

Locations

Countries of recruitment

  • England
  • United Kingdom

Study participating centre

Department of Anaesthesia and Intensive Care
Nottingham
NG7 2UH
United Kingdom

Sponsor information

Department of Health
Government

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Website http://www.dh.gov.uk/Home/fs/en

Funders

Funder type

Hospital/treatment centre

Nottingham University Hospitals NHS Trust (UK)

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to shareNo
IPD sharing plan summaryNot provided at time of registration
Publication and dissemination planNot provided at time of registration
IPD sharing plan

Editorial Notes

18/10/2017: No publications found, study status unverified