The effect of probiotic therapy on nosocomial infections in the critically ill

ISRCTN	ISRCTN51777318
DOI	https://doi.org/10.1186/ISRCTN51777318
Secondary identifying numbers	N0192133923

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Dr D Knight
Scientific

Department of Anaesthesia and Intensive Care
Queens Medical Centre
University Hospital
Nottingham
NG7 2UH
United Kingdom

Study design	Randomised controlled trial
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Hospital
Study type	Prevention
Participant information sheet	Not available in web format, please use the contact details below to request a patient information sheet
Scientific title	The effect of probiotic therapy on nosocomial infections in the critically ill
Study objectives	Does early enteral feeding with probiotics reduce the rate of nosocomial (hospital acquired) infections in the critically ill?
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Infections and Infestations: Nosocomial infections
Intervention	1. Lactobacillus 2. Placebo
Intervention type	Drug
Pharmaceutical study type(s)
Phase	Not Specified
Drug / device / biological / vaccine name(s)	Probiotics
Primary outcome measure	Oropharyngeal nosocomial bacterial carriage rates, nosocomial infection rates, death rates, diarrhoea rates.
Secondary outcome measures	Not provided at time of registration
Overall study start date	07/10/2003
Completion date	31/12/2005

Participant type(s)	Patient
Age group	Not Specified
Sex	Both
Target number of participants	Not provided at time of registration
Key inclusion criteria	Not provided at time of registration
Key exclusion criteria	Does not meet inclusion criteria
Date of first enrolment	07/10/2003
Date of final enrolment	31/12/2005

Department of Anaesthesia and Intensive Care

Nottingham
NG7 2UH
United Kingdom

Department of Health
Government

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Website	http://www.dh.gov.uk/Home/fs/en

Hospital/treatment centre

Nottingham University Hospitals NHS Trust (UK)

No information available

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

18/10/2017: No publications found, study status unverified