Contact information
Type
Scientific
Primary contact
Prof J G F Cleland
ORCID ID
Contact details
Academic Cardiology Department
Cardiology
Castle Hill Hospital
Cottingham
HU16 5JQ
United Kingdom
+44 (0)1482 624083
J.G.Cleland@hull.ac.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N0084113936
Study information
Scientific title
Acronym
Study hypothesis
What rate should the pace-makers be set at to cope with the bradycardia which almost invariably is induced by beta blocker?
Ethics approval
Not provided at time of registration
Study design
Partially single blinded cross over design
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Not Specified
Patient information sheet
Condition
Cardiovascular: Congestive heart failure (CHF)
Intervention
The patients undergo a randomised comparison of the short term effects of different pacing modes.
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measures
Not provided at time of registration
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/03/2000
Overall trial end date
01/03/2003
Reason abandoned
Eligibility
Participant inclusion criteria
Not provided at time of registration
Participant type
Patient
Age group
Not Specified
Gender
Not Specified
Target number of participants
30 patients
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
01/03/2000
Recruitment end date
01/03/2003
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Academic Cardiology Department
Cottingham
HU16 5JQ
United Kingdom
Sponsor information
Organisation
Department of Health
Sponsor details
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
Sponsor type
Government
Website
Funders
Funder type
Government
Funder name
The North and South Bank Research and Development Consortium (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
2006 results in http://www.ncbi.nlm.nih.gov/pubmed/16996845
Publication citations
-
Results
Thackray SD, Ghosh JM, Wright GA, Witte KK, Nikitin NP, Kaye GC, Clark AL, Tweddel A, Cleland JG, The effect of altering heart rate on ventricular function in patients with heart failure treated with beta-blockers., Am. Heart J., 2006, 152, 4, 713.e9-13, doi: 10.1016/j.ahj.2006.07.007.