Condition category
Eye Diseases
Date applied
30/09/2005
Date assigned
30/09/2005
Last edited
03/06/2008
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Mr G.S. Ang

ORCID ID

Contact details

Senior House Officer
Department of Ophthalmology
Norfolk and Norwich University Hospital NHS Trust
Colney
Norwich
NR4 7UY
United Kingdom

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N0547147995

Study information

Scientific title

Acronym

Study hypothesis

Travoprost is a new prostaglandin analogue recently approved for treatment of ocular hypertension and glaucoma.

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Treatment

Patient information sheet

Condition

Eye Diseases: Glaucoma

Intervention

Prospective randomised controlled observer blinded clinical trial.

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

The primary clinical outcome measure is diurnal IOP at follow up phasing: the major comparison is to be made between the IOP for travoprost treatment group and for the non-treatment group.

Secondary outcome measures

Not provided at time of registration

Overall trial start date

01/04/2004

Overall trial end date

01/06/2006

Reason abandoned

Eligibility

Participant inclusion criteria

Adults with normal tension glaucoma.

Participant type

Patient

Age group

Adult

Gender

Not Specified

Target number of participants

25-30 patients

Participant exclusion criteria

1. Patients on systemic medication
2. Patients who have undergone intraocular eye surgery

Recruitment start date

01/04/2004

Recruitment end date

01/06/2006

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Senior House Officer
Norwich
NR4 7UY
United Kingdom

Sponsor information

Organisation

Department of Health

Sponsor details

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
+44 (0)20 7307 2622
dhmail@doh.gsi.org.uk

Sponsor type

Government

Website

http://www.dh.gov.uk/Home/fs/en

Funders

Funder type

Government

Funder name

East Norfolk and Waveney Research Consortium - Norfolk and Norwich University Hospital/Norwich PCT

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Results in http://www.ncbi.nlm.nih.gov/pubmed/18511540

Publication citations

  1. Results

    Ang GS, Kersey JP, Shepstone L, Broadway DC, The effect of travoprost on daytime intraocular pressure in normal tension glaucoma: a randomised controlled trial., Br J Ophthalmol, 2008, 92, 8, 1129-1133, doi: 10.1136/bjo.2007.135269.

Additional files

Editorial Notes