The use of urinary markers to improve adherence to the treatment of osteopoerosis

ISRCTN	ISRCTN54722759
DOI	https://doi.org/10.1186/ISRCTN54722759
Protocol serial number	N0231117494
Sponsor	Department of Health (UK)
Funder	Southampton University Hospitals NHS Trust (UK)

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Dr Muhammad Javaid
Scientific

MRC EEU
Southampton General Hospital
Tremona Road
Southampton
SO16 6YD
United Kingdom

Phone	+44 023 8077 7624
Email	mkj@mrc.soton.ac.uk

Primary study design	Interventional
Study design	Placebo controlled prospective randomized clinical trial
Secondary study design	Randomised controlled trial
Scientific title
Study objectives	Do measurements of bone markers improve patients compliance to therapy?
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Musculoskeletal Diseases: Osteoporosis
Intervention	Urinary markers vs placebo Added July 2008: the trial was stopped due to lack of participants.
Intervention type	Other
Primary outcome measure(s)	Compliance to medication at 1 year, change in bone mineral density at 1 year.
Key secondary outcome measure(s)	Not provided at time of registration
Completion date	31/10/2005
Reason abandoned (if study stopped)	Lack of participants

Participant type(s)	Patient
Age group	Not Specified
Sex	Not Specified
Key inclusion criteria	Patients starting drug therapy for treatment of osteoporosis.
Key exclusion criteria	Not provided at time of registration
Date of first enrolment	01/11/2002
Date of final enrolment	31/10/2005

MRC EEU

Southampton
SO16 6YD
United Kingdom

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan