Condition category
Mental and Behavioural Disorders
Date applied
12/09/2003
Date assigned
12/09/2003
Last edited
02/07/2009
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Sonia Johnson

ORCID ID

Contact details

Department of Psychiatry and Behavioural Sciences
University College London Medical School
Wolfson Buiding
48 Riding House Street
London
W1N 8AA
United Kingdom
+44 020 7527 8805
s.johnson@ucl.ac.uk

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N0053056706

Study information

Scientific title

Acronym

Study hypothesis

The aim of the study is to assess the effectiveness of Assertive Community Treatment (ACT) as a way of engaging individuals with severe mental illnesses who engage poorly with standard community services.

Ethics approval

Camden and Islington Community and Royal Free Hospital local research ethics committees.

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Other

Trial type

Not Specified

Patient information sheet

Condition

Mental and Behavioural Disorders

Intervention

Interviews. Randomised Controlled Trial:
A. Assertive Community Treatment
B. Normal Care

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Assertive Community Treatment (ACT) is an important and promising model, in that it has the potential to meet the needs of a particularly chaotic client group to whom standard community based services currently struggle to deliver services. The results should inform policy makers, local service commissioners and providers of health services in metropolitan areas in the UK.

Secondary outcome measures

Not provided at time of registration

Overall trial start date

01/11/1999

Overall trial end date

31/01/2004

Reason abandoned

Eligibility

Participant inclusion criteria

1. Living in independent or low supported accommodation within the London boroughs of Camden and Islington
2. Under the care of the community mental health team for at least 12 months
3. Identified as having difficulty engaging with standard community care
4. Primary diagnosis of serious mental illness (for example, schizophrenia, schizoaffective disorder, other chronic psychosis, bipolar affective disorder)
5. Recent high use of inpatient care (at least 100 consecutive inpatient days or at least five admissions within the past two years or at least 50 consecutive inpatient days or at least three admissions within the past year)
6. Individuals with concurrent problems from substance misuse or personality disorder were eligible if these were secondary diagnoses

Participant type

Patient

Age group

Not Specified

Gender

Both

Target number of participants

251

Participant exclusion criteria

Patients with organic brain damage

Recruitment start date

01/11/1999

Recruitment end date

31/01/2004

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Department of Psychiatry and Behavioural Sciences
London
W1N 8AA
United Kingdom

Sponsor information

Organisation

Department of Health (UK)

Sponsor details

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Sponsor type

Government

Website

http://www.doh.gov.uk

Funders

Funder type

Government

Funder name

Camden and Islington Health Authority, the King’s Fund, and the

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

Department of Health.

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

1. 2006 results in http://www.ncbi.nlm.nih.gov/pubmed/16543298
2. 2009 results in http://www.ncbi.nlm.nih.gov/pubmed/19567902

Publication citations

  1. Results

    Killaspy H, Bebbington P, Blizard R, Johnson S, Nolan F, Pilling S, King M, The REACT study: randomised evaluation of assertive community treatment in north London., BMJ, 2006, 332, 7545, 815-820, doi: 10.1136/bmj.38773.518322.7C.

  2. Results

    Killaspy H, Kingett S, Bebbington P, Blizard R, Johnson S, Nolan F, Pilling S, King M, Randomised evaluation of assertive community treatment: 3-year outcomes., Br J Psychiatry, 2009, 195, 1, 81-82, doi: 10.1192/bjp.bp.108.059303.

Additional files

Editorial Notes