Contact information
Type
Scientific
Primary contact
Dr Andy Smith
ORCID ID
Contact details
Sunnybrook & Women's College Health Sciences Centre
TSRCC
2075 Bayview Ave.
Room T2-057
Toronto
M4N 3M5
Canada
+1 416 480 4027
andy.smith@sw.ca
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N/A
Study information
Scientific title
Acronym
Study hypothesis
We hypothesise that practice change can be induced among surgeons and pathologists using an adapted social marketing model that utilised the influence of both expert and local opinion leaders (OLs) for colorectal cancer (CRC) in a large geographic area with diverse practice settings.
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Hospitals
Trial type
Quality of life
Patient information sheet
Condition
Colorectal cancer
Intervention
There are three arms in the trial:
Arm 1: Presentations only
Arm 2: Presentations plus opinion leader activation (posters, pocket cards, etc.). There are opinion leaders in all sites visited however, only 42 had opinion leader activation.
Arm 3: The third arm had no opinion leaders identified and no presentations
Intervention type
Other
Phase
Not Applicable
Drug names
Primary outcome measures
Change in practice patterns in that an appropriate number of lymph nodes is retrieved and assessed in order to refer patients appropriately for further treatment
Secondary outcome measures
No secondary outcome measures
Overall trial start date
01/04/2002
Overall trial end date
01/04/2006
Reason abandoned
Eligibility
Participant inclusion criteria
Surgeons and pathologists involved in the care of colorectal cancer that are practising in the province of Ontario, Canada.
Participant type
Patient
Age group
Adult
Gender
Both
Target number of participants
Surgeons (n = 794) and pathologists (n = 449)
Participant exclusion criteria
Retired or semi-retired surgeons and pathologists or physicians who do not care for colorectal cancer patients
Recruitment start date
01/04/2002
Recruitment end date
01/04/2006
Locations
Countries of recruitment
Canada
Trial participating centre
Sunnybrook & Women's College Health Sciences Centre
Toronto
M4N 3M5
Canada
Sponsor information
Organisation
Sunnybrook and Women's College Health Sciences Centre (Canada)
Sponsor details
TSRCC
2075 Bayview Ave.
Room T2-057
Toronto
M4N 3M5
Canada
linda.last@sw.ca
Sponsor type
University/education
Website
Funders
Funder type
Charity
Funder name
The Change Foundation (Canada) (ref: 02064)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Funder name
Ontario Cancer Research Network (Canada) (ref: 02-NOV-0236)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
1. 2006 results: http://www.ncbi.nlm.nih.gov/pubmed/16412251
2. 2008 results: http://www.ncbi.nlm.nih.gov/pubmed/19015462
Publication citations
-
Results
Wright FC, Law CH, Last LD, Klar N, Ryan DP, Smith AJ, A blended knowledge translation initiative to improve colorectal cancer staging [ISRCTN56824239]., BMC Health Serv Res, 2006, 6, 4, doi: 10.1186/1472-6963-6-4.
-
Results
Wright FC, Gagliardi AR, Law CH, Last LD, Klevan AE, Hongjinda S, Stitt LW, Klar N, Ryan DP, Smith AJ, A randomized controlled trial to improve lymph node assessment in stage II colon cancer., Arch Surg, 2008, 143, 11, 1050-5; discussion 1055, doi: 10.1001/archsurg.143.11.1050.