Condition category
Cancer
Date applied
13/09/2005
Date assigned
28/09/2005
Last edited
17/12/2008
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Andy Smith

ORCID ID

Contact details

Sunnybrook & Women's College Health Sciences Centre
TSRCC
2075 Bayview Ave.
Room T2-057
Toronto
M4N 3M5
Canada
+1 416 480 4027
andy.smith@sw.ca

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N/A

Study information

Scientific title

Acronym

Study hypothesis

We hypothesise that practice change can be induced among surgeons and pathologists using an adapted social marketing model that utilised the influence of both expert and local opinion leaders (OLs) for colorectal cancer (CRC) in a large geographic area with diverse practice settings.

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Hospitals

Trial type

Quality of life

Patient information sheet

Condition

Colorectal cancer

Intervention

There are three arms in the trial:
Arm 1: Presentations only
Arm 2: Presentations plus opinion leader activation (posters, pocket cards, etc.). There are opinion leaders in all sites visited however, only 42 had opinion leader activation.
Arm 3: The third arm had no opinion leaders identified and no presentations

Intervention type

Other

Phase

Not Applicable

Drug names

Primary outcome measures

Change in practice patterns in that an appropriate number of lymph nodes is retrieved and assessed in order to refer patients appropriately for further treatment

Secondary outcome measures

No secondary outcome measures

Overall trial start date

01/04/2002

Overall trial end date

01/04/2006

Reason abandoned

Eligibility

Participant inclusion criteria

Surgeons and pathologists involved in the care of colorectal cancer that are practising in the province of Ontario, Canada.

Participant type

Patient

Age group

Adult

Gender

Both

Target number of participants

Surgeons (n = 794) and pathologists (n = 449)

Participant exclusion criteria

Retired or semi-retired surgeons and pathologists or physicians who do not care for colorectal cancer patients

Recruitment start date

01/04/2002

Recruitment end date

01/04/2006

Locations

Countries of recruitment

Canada

Trial participating centre

Sunnybrook & Women's College Health Sciences Centre
Toronto
M4N 3M5
Canada

Sponsor information

Organisation

Sunnybrook and Women's College Health Sciences Centre (Canada)

Sponsor details

TSRCC
2075 Bayview Ave.
Room T2-057
Toronto
M4N 3M5
Canada
linda.last@sw.ca

Sponsor type

University/education

Website

Funders

Funder type

Charity

Funder name

The Change Foundation (Canada) (ref: 02064)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

Ontario Cancer Research Network (Canada) (ref: 02-NOV-0236)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

1. 2006 results: http://www.ncbi.nlm.nih.gov/pubmed/16412251
2. 2008 results: http://www.ncbi.nlm.nih.gov/pubmed/19015462

Publication citations

  1. Results

    Wright FC, Law CH, Last LD, Klar N, Ryan DP, Smith AJ, A blended knowledge translation initiative to improve colorectal cancer staging [ISRCTN56824239]., BMC Health Serv Res, 2006, 6, 4, doi: 10.1186/1472-6963-6-4.

  2. Results

    Wright FC, Gagliardi AR, Law CH, Last LD, Klevan AE, Hongjinda S, Stitt LW, Klar N, Ryan DP, Smith AJ, A randomized controlled trial to improve lymph node assessment in stage II colon cancer., Arch Surg, 2008, 143, 11, 1050-5; discussion 1055, doi: 10.1001/archsurg.143.11.1050.

Additional files

Editorial Notes