Condition category
Surgery
Date applied
12/09/2003
Date assigned
12/09/2003
Last edited
11/10/2016
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr MH Nathanson

ORCID ID

Contact details

Department of Anaethesia
C Floor
University Hospital
Nottingham
NG7 2UH
United Kingdom

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N0192080350

Study information

Scientific title

Sevoflurane inhalational introduction in the elderly: a comparison with intravenous induction

Acronym

Study hypothesis

The aim of the study is to compare the effects of an inhalational induction of anaesthesia with sevoflurane with an intravenous induction in elderly patients. In particular, we will assess the effects on cardiovascular parameters (heart rate, blood pressure), and cerebral blood flow velocity. We hypothesise that compared with an intravenous induction an inhalational induction will be more stable.

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Hospitals

Trial type

Treatment

Patient information sheet

Not available in web format, please use contact details to request a participant information sheet

Condition

Anaesthesia

Intervention

Randomised controlled trial:
1. Inhalational induction of anaesthesia with sevoflurane
2. Intravenous induction of anaesthesia with sevoflurane

Intervention type

Drug

Phase

Not Applicable

Drug names

Sevoflurane

Primary outcome measures

Change in blood pressure and cerebral flow velocity during induction of anaesthesia compared to baseline values.

Secondary outcome measures

Not provided at time of registration

Overall trial start date

20/08/2001

Overall trial end date

14/11/2002

Reason abandoned

Eligibility

Participant inclusion criteria

Total number of subjects = 40

Participant type

Patient

Age group

Senior

Gender

Both

Target number of participants

40

Participant exclusion criteria

Not provided at time of registration

Recruitment start date

20/08/2001

Recruitment end date

14/11/2002

Locations

Countries of recruitment

United Kingdom

Trial participating centre

University Hospital
Nottingham
NG7 2UH
United Kingdom

Sponsor information

Organisation

Department of Health (UK)

Sponsor details

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Sponsor type

Government

Website

http://www.doh.gov.uk

Funders

Funder type

Hospital/treatment centre

Funder name

Queens Medical Centre, Nottingham University Hospital NHS Trust (UK) - NHS R&D Support Funding

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

Abbott Laboratories (UK)

Alternative name(s)

Funding Body Type

private sector organisation

Funding Body Subtype

corporate

Location

United States of America

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Publication citations

Additional files

Editorial Notes

11/10/2016: No publications found, verifying study status with principal investigator.