Sevoflurane inhalational introduction in the elderly: a comparison with intravenous induction
| ISRCTN | ISRCTN61123518 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN61123518 |
| Secondary identifying numbers | N0192080350 |
- Submission date
- 12/09/2003
- Registration date
- 12/09/2003
- Last edited
- 11/10/2016
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Surgery
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr MH Nathanson
Scientific
Scientific
Department of Anaethesia
C Floor, University Hospital
Nottingham
NG7 2UH
United Kingdom
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Treatment |
| Participant information sheet | Not available in web format, please use contact details to request a participant information sheet |
| Scientific title | Sevoflurane inhalational introduction in the elderly: a comparison with intravenous induction |
| Study objectives | The aim of the study is to compare the effects of an inhalational induction of anaesthesia with sevoflurane with an intravenous induction in elderly patients. In particular, we will assess the effects on cardiovascular parameters (heart rate, blood pressure), and cerebral blood flow velocity. We hypothesise that compared with an intravenous induction an inhalational induction will be more stable. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Anaesthesia |
| Intervention | Randomised controlled trial: 1. Inhalational induction of anaesthesia with sevoflurane 2. Intravenous induction of anaesthesia with sevoflurane |
| Intervention type | Drug |
| Pharmaceutical study type(s) | |
| Phase | Not Applicable |
| Drug / device / biological / vaccine name(s) | Sevoflurane |
| Primary outcome measure | Change in blood pressure and cerebral flow velocity during induction of anaesthesia compared to baseline values. |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 20/08/2001 |
| Completion date | 14/11/2002 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Senior |
| Sex | Both |
| Target number of participants | 40 |
| Key inclusion criteria | Total number of subjects = 40 |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 20/08/2001 |
| Date of final enrolment | 14/11/2002 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
University Hospital
Nottingham
NG7 2UH
United Kingdom
NG7 2UH
United Kingdom
Sponsor information
Department of Health (UK)
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Website | http://www.doh.gov.uk |
|---|
Funders
Funder type
Hospital/treatment centre
Queens Medical Centre, Nottingham University Hospital NHS Trust (UK) - NHS R&D Support Funding
No information available
Abbott Laboratories (UK)
Government organisation / For-profit companies (industry)
Government organisation / For-profit companies (industry)
- Alternative name(s)
- Abbott, Abbott U.S., Abbott Alkaloidal Company
- Location
- United States of America
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Editorial Notes
11/10/2016: No publications found, verifying study status with principal investigator.
