Plain English Summary
Background and study aims
Participation in the NHS Bowel Cancer Screening Programme is low, particularly in people from a lower socioeconomic status. The information materials provided to people can be difficult to understand for people with lower levels of literacy, and may therefore inadvertently discourage participation. This study aims to test a low literacy information booklet to be incorporated within the NHS Bowel Cancer Screening Programme.
Who can participate?
Patients registered at four GP practices, aged 45-59
What does the study involve?
Participants are randomly allocated to be sent either the standard information materials, or the standard materials along with a low literacy information booklet.
What are the possible benefits and risks of participating?
Participants learn about the topic of bowel cancer and bowel cancer screening. There are no risks to taking part in the study.
Where is the study run from?
CRUK & UCL Cancer Trials Centre (UK)
When is the study starting and how long is it expected to run for?
July to September 2012
Who is funding the study?
National Institute for Health Research (UK)
Who is the main contact?
Mr Samuel Smith
CR UK & UCL Cancer Trials Centre
90 Tottenham Court Road
Evaluation of a 'gist-based' information leaflet to be used in the NHS Bowel Cancer Screening Programme: a randomised study
Bowel cancer is the second most common cause of cancer death in the UK. Finding cancer early can save lives; therefore, in 2006, the NHS launched a Bowel Cancer Screening Programme (BCSP). In England, the BCSP offers screening to 60-69 year olds (up to 74 years in some areas). Screening involves completing a stool sample test kit, the faecal occult blood test (FOB) at home. Recent data suggests that only 54% of those offered the FOB test choose to do it. However, this figure varies from more than 60% in the most socially advantaged groups to less than 35% in the most disadvantaged groups. The current study is part of a larger research programme (the ASCEND Project) funded by the National Institute of Health Research (NIHR) that aims to reduce this difference in uptake rates between social groups. This study specifically aims to assess the influence of a gist-based leaflet developed by the research team, on future intentions to use the FOB test. Participants aged 45-59 (who have not yet taken part in the BCSP), will be recruited through GP practices. All participants will be sent the usual BCSP information leaflet 'Bowel Cancer Screening: The Facts', while the intervention group will also receive a gist-based leaflet. A questionnaire will ask about the participants views (e.g. intention to be screened, comprehension, attitudes, beliefs) on bowel cancer and bowel cancer screening. Answers will be compared between the two groups in order to assess the impact of the gist-based leaflet.
NRES Committee Yorkshire & The Humber - Leeds West, 12/YH/0106; First MREC approval date 07/02/2012
Randomised; Interventional; Design type: Not specified
Primary study design
Secondary study design
Randomised controlled trial
Patient information sheet
Not available in web format, please use the contact details below to request a patient information sheet
Topic: Primary Care Research Network for England; Subtopic: Not Assigned; Disease: All Diseases
All participants will be sent the usual BCSP information leaflet 'Bowel Cancer Screening: The Facts', while the intervention group will also receive a gist-based leaflet.
Primary outcome measure
Intention to be screened
Secondary outcome measures
Not provided at time of registration
Overall trial start date
Overall trial end date
Reason abandoned (if study stopped)
Participant inclusion criteria
1. Registered with a GP Practice
2. Aged between 45-59, Male & Female
Target number of participants
Planned Sample Size: 840; UK Sample Size: 840
Participant exclusion criteria
1. Patients whom are unable or do not wish to provide informed consent
2. Patients whom the GP advises should not be approached (e.g. recent diagnosis of cancer or other significant illness, terminally ill, learning disability, already receives regular colonoscopies)
3. Patients who are not able to read English
Recruitment start date
Recruitment end date
Countries of recruitment
Trial participating centre
CRUK & UCL Cancer Trials Centre
University College London (UK)
c/o Dave Wilson
National Institute for Health Research - Programme Grant for Applied Research (PGfAR)
Funding Body Type
Funding Body Subtype
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not expected to be available
Basic results (scientific)
2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/25253443