Acute effects of smoking and oral nicotine on blood haemostatis using thromboelastography
| ISRCTN | ISRCTN63224732 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN63224732 |
| Secondary identifying numbers | N0436130424 |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 02/06/2017
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Haematological Disorders
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Mr R Fearn
Scientific
Scientific
Obstetric Anaesthesia
Gledhow Wing
Leeds Teaching Hospitals NHS Trust
Beckett Street
Leeds
LS9 7TF
United Kingdom
| Phone | +44 (0)113 243 3144 |
|---|---|
| r&d@leedsth.nhs.uk |
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Other |
| Scientific title | Acute effects of smoking and oral nicotine on blood haemostatis using thromboelastography |
| Study objectives | 1. To determine the acute effects of smoking on whole blood coagulation 2. To determine the acute effects of inhaled nicotine on whole blood coagulation |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Haemostasis |
| Intervention | Randomised controlled trial: 1. Smoking a cigarette versus smoking a sham cigarette 2. Inhaling from a nicotine inhaler versus inhaler from a inhaler with no nicotine |
| Intervention type | Other |
| Primary outcome measure | Thromboelastography variables: 1. R-value 2. K-value 3. Angle 4. Maximum amplitude 5. Coagulation index |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 30/09/2002 |
| Completion date | 30/07/2003 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Both |
| Target number of participants | Not provided at time of registration |
| Key inclusion criteria | Healthy adult smokers who fall into American Society of Anaesthesiologists classes 1 and 2 |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 30/09/2002 |
| Date of final enrolment | 30/07/2003 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
Obstetric Anaesthesia
Leeds
LS9 7TF
United Kingdom
LS9 7TF
United Kingdom
Sponsor information
Department of Health
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Website | http://www.dh.gov.uk/Home/fs/en |
|---|
Funders
Funder type
Government
Leeds Teaching Hospitals NHS Trust (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Editorial Notes
02/06/2017: No publications found in PubMed, verifying study status with principal investigator
