Condition category
Circulatory System
Date applied
15/06/2006
Date assigned
06/07/2006
Last edited
10/04/2012
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Mr Richard Lowrie

ORCID ID

Contact details

Primary Care Research and Development Directorate
Gartnavel Royal Hospital
1055 Great Western Road
Glasgow
Scotland
G12 OXH
United Kingdom
+44 (0)141 211 3690
Richard.lowrie@gartnavel.glacomen.scot.nhs.uk

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

04/SO701/8

Study information

Scientific title

Acronym

Study hypothesis

Pharmacists in primary care can prevent hospitalisation and early death through medication review

Ethics approval

2004; Greater Glasgow Primary Care NHS Trust Local Research Ethics Committee

Study design

Randomised controlled trial with cost effectiveness analysis

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Other

Trial type

Prevention

Patient information sheet

Not available in web format, please use the contact details below to request a patient information sheet

Condition

Chronic heart failure

Intervention

Practices in the control group, in common with intervention group, receive a complete disease register for patients with a diagnosis of chronic heart failure due to left ventricular systolic dysfunction. Control group practices do not receive any further pharmacist led support. Intervention practices receive pharmacist medication review for their patients with heart failure.

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Death or heart failure hospitalisations

Secondary outcome measures

Survival times until occurrence of first heart failure hospitalisation or death

Overall trial start date

01/05/2004

Overall trial end date

01/06/2009

Reason abandoned

Eligibility

Participant inclusion criteria

1. Consenting practices
2. Patients with confirmed left ventricular systolic dysfunction (LSVD) providing written consent

Participant type

Patient

Age group

Adult

Gender

Both

Target number of participants

2400

Participant exclusion criteria

1. Non LVSD
2. Not chronic heart failure
3. Renal failure requiring dialysis
4. Patient under enhanced form of Primary Care

Recruitment start date

01/05/2004

Recruitment end date

01/06/2009

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Primary Care Research and Development Directorate
Scotland
G12 OXH
United Kingdom

Sponsor information

Organisation

Greater Glasgow Primary Care NHS Trust (UK)

Sponsor details

Primary Care Research and Development Directorate
Gartnavel Royal Hospital
1055 Great Western Road
Glasgow
Scotland
G12 OXH
United Kingdom

Sponsor type

Hospital/treatment centre

Website

Funders

Funder type

Hospital/treatment centre

Funder name

NHS Glasgow Research and Development

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

1.2012 results in http://www.ncbi.nlm.nih.gov/pubmed/22083873

Publication citations

  1. Lowrie R, Mair FS, Greenlaw N, Forsyth P, Jhund PS, McConnachie A, Rae B, McMurray JJ, , Pharmacist intervention in primary care to improve outcomes in patients with left ventricular systolic dysfunction., Eur. Heart J., 2012, 33, 3, 314-324, doi: 10.1093/eurheartj/ehr433.

Additional files

Editorial Notes