Blood transfusions for preterm infants and free radicals
| ISRCTN | ISRCTN72984863 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN72984863 |
| Secondary identifying numbers | RHC18070 |
- Submission date
- 23/01/2004
- Registration date
- 23/01/2004
- Last edited
- 03/12/2008
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Neonatal Diseases
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Alan Weindling
Scientific
Scientific
Liverpool Women's Hospital
Neonatal Unit
Crown Street
Liverpool
L8 7SS
United Kingdom
| Phone | +44 (0)151 702 4093 |
|---|
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Not specified |
| Study type | Not Specified |
| Scientific title | |
| Study objectives | Does a blood transfusion in preterm infants cause free radical release? |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Neonatal diseases |
| Intervention | Group 1 will have their need for blood transfusion monitored according to a standard protocol. Group 2 will have measurements of forearm fractional oxygen extraction (FOE) to guide their need for transfusions. |
| Intervention type | Other |
| Primary outcome measure | The primary outcome measure will be peak ODFR activity. |
| Secondary outcome measures | A secondary outcome will be the number of days on the neonatal unit, retinopathy or prematurity, preventricular haemorrhage and periventricular leukomalacia and necrotising enterocolitis. |
| Overall study start date | 01/02/1998 |
| Completion date | 01/08/1999 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Neonate |
| Sex | Not Specified |
| Target number of participants | Not provided at time of registration |
| Key inclusion criteria | Preterm infants |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/02/1998 |
| Date of final enrolment | 01/08/1999 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
Liverpool Women's Hospital
Liverpool
L8 7SS
United Kingdom
L8 7SS
United Kingdom
Sponsor information
NHS R&D Regional Programme Register - Department of Health (UK)
Government
Government
The Department of Health
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Phone | +44 (0)20 7307 2622 |
|---|---|
| dhmail@doh.gsi.org.uk | |
| Website | http://www.doh.gov.uk |
Funders
Funder type
Government
NHS Executive North West (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/01/2002 | Yes | No |
