Condition category
Cancer
Date applied
08/11/2005
Date assigned
15/11/2005
Last edited
24/07/2014
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Lillian Siu

ORCID ID

Contact details

Princess Margaret Hospital
610 University Avenue
Toronto
M5G 2M9
Canada
+1 416 946 2911
lillian.siu@uhn.on.ca

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N/A

Study information

Scientific title

Acronym

Study hypothesis

We hypothesize that a simple, low-tech assistance device, such as daily pill boxes, as compared to conventional pill bottles, will increase the rate of patientsÂ’ adherence to oral chemotherapy.

Ethics approval

UHN Research Ethics Board, 02/05/2005, UHN REB 05-0199-CE

Study design

Randomized cross-over design

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Not Specified

Patient information sheet

Condition

Advanced solid tumors

Intervention

Daily pill boxes versus conventional pill bottles for packaging

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Patient adherence was similiar.

Secondary outcome measures

Patients more satisfied with daily pill boxes than conventional pill bottles.

Overall trial start date

01/04/2005

Overall trial end date

30/06/2005

Reason abandoned

Eligibility

Participant inclusion criteria

Patients were included in this study if they:
1. Provided informed consent
2. Were capable of reading and writing in English
3. Were greater than 18 years of age with solid tumors
4. Were planned to receive at least 2 consecutive cycles of capecitabine

Participant type

Patient

Age group

Adult

Gender

Both

Target number of participants

25

Participant exclusion criteria

Patients taking other oral anticancer medications such as temozolomide, tamoxifen and arimidex, were not felt to be suitable for the present study since these oral medications are already dispensed in unit dose packages.

Recruitment start date

01/04/2005

Recruitment end date

30/06/2005

Locations

Countries of recruitment

Canada

Trial participating centre

Princess Margaret Hospital
Toronto
M5G 2M9
Canada

Sponsor information

Organisation

Princess Margaret Hospital (Canada)

Sponsor details

610 University Avenue
Toronto
M5G 2M9
Canada
+1 416 946 2911
lillian.siu@uhn.on.ca

Sponsor type

Hospital/treatment centre

Website

Funders

Funder type

Hospital/treatment centre

Funder name

Dr Lillian Siu's research funds

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2007 results in: http://www.ncbi.nlm.nih.gov/pubmed/17587364

Publication citations

  1. Results

    Macintosh PW, Pond GR, Pond BJ, Leung V, Siu LL, A comparison of patient adherence and preference of packaging method for oral anticancer agents using conventional pill bottles versus daily pill boxes., Eur J Cancer Care (Engl), 2007, 16, 4, 380-386, doi: 10.1111/j.1365-2354.2006.00758.x.

Additional files

Editorial Notes