Contact information
Type
Scientific
Primary contact
Dr Lillian Siu
ORCID ID
Contact details
Princess Margaret Hospital
610 University Avenue
Toronto
M5G 2M9
Canada
+1 416 946 2911
lillian.siu@uhn.on.ca
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N/A
Study information
Scientific title
Acronym
Study hypothesis
We hypothesize that a simple, low-tech assistance device, such as daily pill boxes, as compared to conventional pill bottles, will increase the rate of patientsÂ’ adherence to oral chemotherapy.
Ethics approval
UHN Research Ethics Board, 02/05/2005, UHN REB 05-0199-CE
Study design
Randomized cross-over design
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Not Specified
Patient information sheet
Condition
Advanced solid tumors
Intervention
Daily pill boxes versus conventional pill bottles for packaging
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measures
Patient adherence was similiar.
Secondary outcome measures
Patients more satisfied with daily pill boxes than conventional pill bottles.
Overall trial start date
01/04/2005
Overall trial end date
30/06/2005
Reason abandoned
Eligibility
Participant inclusion criteria
Patients were included in this study if they:
1. Provided informed consent
2. Were capable of reading and writing in English
3. Were greater than 18 years of age with solid tumors
4. Were planned to receive at least 2 consecutive cycles of capecitabine
Participant type
Patient
Age group
Adult
Gender
Both
Target number of participants
25
Participant exclusion criteria
Patients taking other oral anticancer medications such as temozolomide, tamoxifen and arimidex, were not felt to be suitable for the present study since these oral medications are already dispensed in unit dose packages.
Recruitment start date
01/04/2005
Recruitment end date
30/06/2005
Locations
Countries of recruitment
Canada
Trial participating centre
Princess Margaret Hospital
Toronto
M5G 2M9
Canada
Sponsor information
Organisation
Princess Margaret Hospital (Canada)
Sponsor details
610 University Avenue
Toronto
M5G 2M9
Canada
+1 416 946 2911
lillian.siu@uhn.on.ca
Sponsor type
Hospital/treatment centre
Website
Funders
Funder type
Hospital/treatment centre
Funder name
Dr Lillian Siu's research funds
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
2007 results in: http://www.ncbi.nlm.nih.gov/pubmed/17587364
Publication citations
-
Results
Macintosh PW, Pond GR, Pond BJ, Leung V, Siu LL, A comparison of patient adherence and preference of packaging method for oral anticancer agents using conventional pill bottles versus daily pill boxes., Eur J Cancer Care (Engl), 2007, 16, 4, 380-386, doi: 10.1111/j.1365-2354.2006.00758.x.