Condition category
Cancer
Date applied
02/12/2004
Date assigned
06/12/2004
Last edited
14/08/2009
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Neil Blumberg

ORCID ID

Contact details

601 Elmwood Avenue
Box 608
Rochester
14642
United States of America
+1 585 275 9656
neil_blumberg@urmc.rochester.edu

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N/A

Study information

Scientific title

Acronym

Study hypothesis

Not provided at time of registration

Ethics approval

Not provided at time of registration

Study design

Randomised active controlled parallel group trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Hospitals

Trial type

Treatment

Patient information sheet

Condition

Acute Leukemia

Intervention

The control intervention was leukocyte reduced red cell and platelet transfusions, the standard practice in most hospitals.
The experimental intervention was leukocyte reduced red cell and platelet transfusions that had also been plasma reduced by washing.

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Added 14/08/09:
1. Platelet transfusion refractoriness
2. Infectious and bleeding complications
3. Overall survival.

Secondary outcome measures

Not provided at time of registration

Overall trial start date

01/01/1991

Overall trial end date

31/12/1994

Reason abandoned

Eligibility

Participant inclusion criteria

Adult patients with acute leukemia undergoing full dose remission induction chemotherapy.

Participant type

Patient

Age group

Adult

Gender

Not Specified

Target number of participants

43

Participant exclusion criteria

Does not match inclusion criteria

Recruitment start date

01/01/1991

Recruitment end date

31/12/1994

Locations

Countries of recruitment

United States of America

Trial participating centre

601 Elmwood Avenue
Rochester
14642
United States of America

Sponsor information

Organisation

University of Rochester (USA)

Sponsor details

601 Elmwood Avenue
Rochester
14642
United States of America
neil_blumberg@urmc.rochester.edu

Sponsor type

University/education

Website

Funders

Funder type

University/education

Funder name

University of Rochester (USA)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

CaridianBCT Inc. (formerly Gambro BCT Inc.) (USA)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2004 results in http://www.ncbi.nlm.nih.gov/pubmed/15588315

Publication citations

  1. Results

    Blumberg N, Heal JM, Rowe JM, A randomized trial of washed red blood cell and platelet transfusions in adult acute leukemia [ISRCTN76536440]., BMC Blood Disord, 2004, 4, 1, 6, doi: 10.1186/1471-2326-4-6.

Additional files

Editorial Notes