Washed blood components in adult acute leukemia
| ISRCTN | ISRCTN76536440 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN76536440 |
| Secondary identifying numbers | N/A |
- Submission date
- 02/12/2004
- Registration date
- 06/12/2004
- Last edited
- 14/08/2009
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Cancer
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Neil Blumberg
Scientific
Scientific
601 Elmwood Avenue
Box 608
Rochester
14642
United States of America
| Phone | +1 585 275 9656 |
|---|---|
| neil_blumberg@urmc.rochester.edu |
Study information
| Study design | Randomised active controlled parallel group trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Treatment |
| Scientific title | |
| Study objectives | Not provided at time of registration |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Acute Leukemia |
| Intervention | The control intervention was leukocyte reduced red cell and platelet transfusions, the standard practice in most hospitals. The experimental intervention was leukocyte reduced red cell and platelet transfusions that had also been plasma reduced by washing. |
| Intervention type | Other |
| Primary outcome measure | Added 14/08/09: 1. Platelet transfusion refractoriness 2. Infectious and bleeding complications 3. Overall survival. |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/01/1991 |
| Completion date | 31/12/1994 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Not Specified |
| Target number of participants | 43 |
| Key inclusion criteria | Adult patients with acute leukemia undergoing full dose remission induction chemotherapy. |
| Key exclusion criteria | Does not match inclusion criteria |
| Date of first enrolment | 01/01/1991 |
| Date of final enrolment | 31/12/1994 |
Locations
Countries of recruitment
- United States of America
Study participating centre
601 Elmwood Avenue
Rochester
14642
United States of America
14642
United States of America
Sponsor information
University of Rochester (USA)
University/education
University/education
601 Elmwood Avenue
Rochester
14642
United States of America
| neil_blumberg@urmc.rochester.edu | |
"ROR" |
https://ror.org/022kthw22 |
Funders
Funder type
University/education
University of Rochester (USA)
No information available
CaridianBCT Inc. (formerly Gambro BCT Inc.) (USA)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 10/12/2004 | Yes | No |
