Condition category
Not Applicable
Date applied
25/04/2003
Date assigned
25/04/2003
Last edited
27/08/2009
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Arnold Zermansky

ORCID ID

Contact details

School of Healthcare Studies
University of Leeds
Division of Academic Pharmacy Practice
Room 2.23 Baines Wing
PO Box 214
Leeds
LS2 9UT
United Kingdom
+44 (0)113 3431340
zermansky@btinternet.com

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

HTA 93/22/09

Study information

Scientific title

Acronym

Study hypothesis

This randomised controlled clinical trial will examine whether a suitably experienced pharmacist can conduct effective clinical medication review of patients on repeat prescriptions. The study will compare this approach with a control group who will be part of the normal review mechanisms for repeat prescriptions. The pharmacist will be an experienced clinical pharmacist with the appropriate clinical and consultation skills.
The objective is to assess whether clinical medication review by a pharmacist is a cost-effective method for improving the extent and quality of clinical control of repeat prescribing, compared with that achieved by the practices' normal procedures.

Ethics approval

Not provided at time of registration.

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Not Specified

Patient information sheet

Condition

Repeat prescriptions

Intervention

A total of 1200 patients from four practices will be randomised to the active or control group. Patients in the active group will be called for an appointment with the pharmacist at the surgery. The pharmacist will assess the continuing appropriateness of the medication regime and make appropriate recommendations (in conjunction with the GP). The control group will receive standard care.

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

The primary outcome was the number of repeat medication changes per patient over a 12-month period. The secondary outcome was the effect on the medication costs. The intervention group was compared with the control group to see whether a review had taken place, the numbers of medication changes, the numbers of repeat medications and the numbers of dosage times. The effects of the medication review clinics were considered in relation to practice consultations, outpatient consultations, hospital admissions and deaths from any cause. The number and nature of the pharmacist¿s interventions and recommendations were recorded, together with whether the recommendations were accepted by the GP.

Secondary outcome measures

Not provided at time of registration.

Overall trial start date

01/03/1999

Overall trial end date

31/03/2001

Reason abandoned

Eligibility

Participant inclusion criteria

Not provided at time of registration.

Participant type

Patient

Age group

Not Specified

Gender

Both

Target number of participants

1200

Participant exclusion criteria

Not provided at time of registration.

Recruitment start date

01/03/1999

Recruitment end date

31/03/2001

Locations

Countries of recruitment

United Kingdom

Trial participating centre

School of Healthcare Studies
Leeds
LS2 9UT
United Kingdom

Sponsor information

Organisation

Department of Health (UK)

Sponsor details

Quarry House
Quarry Hill
Leeds
LS2 7UE
United Kingdom
+44 (0)1132 545 843
Sheila.Greener@doh.gsi.gov.uk

Sponsor type

Government

Website

http://www.dh.gov.uk/en/index.htm

Funders

Funder type

Government

Funder name

NIHR Health Technology Assessment Programme - HTA (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2001 results in http://www.ncbi.nlm.nih.gov/pubmed/11739221

Publication citations

  1. Results

    Zermansky AG, Petty DR, Raynor DK, Freemantle N, Vail A, Lowe CJ, Randomised controlled trial of clinical medication review by a pharmacist of elderly patients receiving repeat prescriptions in general practice., BMJ, 2001, 323, 7325, 1340-1343.

Additional files

Editorial Notes