Condition category
Skin and Connective Tissue Diseases
Date applied
25/02/2005
Date assigned
10/05/2005
Last edited
09/02/2010
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Colin Lyons

ORCID ID

Contact details

68 Engadine Street
London
SW18 5DA
United Kingdom
+44 (0)7810 39 1917
colin.Lyons@gp-e85003.nhs.uk

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N/A

Study information

Scientific title

Acronym

Study hypothesis

The study compares laser treatment (pulsed dye laser at 585 nm; N-Lite® to 'best conventional treatment' for inflammatory active acne in primary care. The hypothesis is that laser works better, faster and cheaper.

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

GP practices

Trial type

Treatment

Patient information sheet

Condition

Acne vulgaris

Intervention

1. Pulsed-dye laser at 585 nm
2. Lymecycline orally & isotretinoin gel topically

Intervention type

Drug

Phase

Not Applicable

Drug names

Lymecycline orally & isotretinoin gel topically

Primary outcome measures

Improvement after 3 months in both groups using the Leeds revised grading system

Secondary outcome measures

Patient satisfaction, compliance, cost

Overall trial start date

01/02/2005

Overall trial end date

31/10/2005

Reason abandoned

Eligibility

Participant inclusion criteria

Age 16-45 with moderate active inflammatory acne vulgaris

Participant type

Patient

Age group

Adult

Gender

Both

Target number of participants

40

Participant exclusion criteria

Not provided at time of registration

Recruitment start date

01/02/2005

Recruitment end date

31/10/2005

Locations

Countries of recruitment

United Kingdom

Trial participating centre

68 Engadine Street
London
SW18 5DA
United Kingdom

Sponsor information

Organisation

West London Research Network (WeLReN) (UK)

Sponsor details

Reynolds Building
3rd Floor
Imperial College
St Dunstan's Road
London
W6 8RP
United Kingdom
+44 (0)20 8746 8000
r.banarsee@imperial.ac.uk

Sponsor type

Government

Website

Funders

Funder type

Government

Funder name

West London Research Network (WeLReN) (UK)

Alternative name(s)

WeLReN

Funding Body Type

private sector organisation

Funding Body Subtype

other non-profit

Location

United Kingdom

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

1. 2009 Outcome measures in acne vulgaris: systematic review in http://www.ncbi.nlm.nih.gov/pubmed/19067711
2. National Knowledge Week on Acne Vulgaris - Invited commentary in http://www.library.nhs.uk/skin/Page.aspx?pagename=ACNECAR

Publication citations

  1. Barratt H, Hamilton F, Car J, Lyons C, Layton A, Majeed A, Outcome measures in acne vulgaris: systematic review., Br. J. Dermatol., 2009, 160, 1, 132-136, doi: 10.1111/j.1365-2133.2008.08819.x.

Additional files

Editorial Notes