Condition category
Respiratory
Date applied
19/07/2005
Date assigned
21/09/2005
Last edited
04/01/2011
Prospective/Retrospective
Retrospectively registered
Overall trial status
Stopped
Recruitment status
Stopped

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Parviz Habibi

ORCID ID

Contact details

Imperial College London
Norfolk Place
London
W21PG
United Kingdom

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

AL001

Study information

Scientific title

Acronym

CHEST

Study hypothesis

Heliox + oxygen driven continuous positive airway pressure (CPAP) reduces work of breathing and improves oxygenation and carbon dioxide clearance more than air + oxygen driven CPAP

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Treatment

Patient information sheet

Condition

Respiratory distress requiring CPAP

Intervention

Heliox + oxygen driven continuous positive airway pressure (CPAP) versus air + oxygen driven CPAP.

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Work of breathing

Secondary outcome measures

Oxygenation, carbon dioxide clearance

Overall trial start date

01/09/2005

Overall trial end date

01/03/2007

Reason abandoned

Lack of funding

Eligibility

Participant inclusion criteria

Children under 1 year of age with respiratory distress requiring CPAP

Participant type

Patient

Age group

Child

Gender

Both

Target number of participants

20

Participant exclusion criteria

Refusing consent, pneumothorax, FiO2 >0.6, imminent intubation, respiratory failure

Recruitment start date

01/09/2005

Recruitment end date

01/03/2007

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Imperial College London
London
W21PG
United Kingdom

Sponsor information

Organisation

Imperial College London (UK)

Sponsor details

Norfolk Place
London
W21PG
United Kingdom

Sponsor type

University/education

Website

Funders

Funder type

Industry

Funder name

Gas will be provided by BOC Ltd. Equipment and application fees will be provided by Viasys

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Publication citations

Additional files

Editorial Notes