CHEST - Pilot Study CPAP: Heliox Effects on Stability and Therapeutics
| ISRCTN | ISRCTN82423314 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN82423314 |
| Secondary identifying numbers | AL001 |
- Submission date
- 19/07/2005
- Registration date
- 21/09/2005
- Last edited
- 04/01/2011
- Recruitment status
- Stopped
- Overall study status
- Stopped
- Condition category
- Respiratory
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Parviz Habibi
Scientific
Scientific
Imperial College London
Norfolk Place
London
W21PG
United Kingdom
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Not specified |
| Study type | Treatment |
| Scientific title | |
| Study acronym | CHEST |
| Study objectives | Heliox + oxygen driven continuous positive airway pressure (CPAP) reduces work of breathing and improves oxygenation and carbon dioxide clearance more than air + oxygen driven CPAP |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Respiratory distress requiring CPAP |
| Intervention | Heliox + oxygen driven continuous positive airway pressure (CPAP) versus air + oxygen driven CPAP. |
| Intervention type | Other |
| Primary outcome measure | Work of breathing |
| Secondary outcome measures | Oxygenation, carbon dioxide clearance |
| Overall study start date | 01/09/2005 |
| Completion date | 01/03/2007 |
| Reason abandoned (if study stopped) | Lack of funding |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Child |
| Upper age limit | 1 Year |
| Sex | Both |
| Target number of participants | 20 |
| Key inclusion criteria | Children under 1 year of age with respiratory distress requiring CPAP |
| Key exclusion criteria | Refusing consent, pneumothorax, FiO2 >0.6, imminent intubation, respiratory failure |
| Date of first enrolment | 01/09/2005 |
| Date of final enrolment | 01/03/2007 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
Imperial College London
London
W21PG
United Kingdom
W21PG
United Kingdom
Sponsor information
Imperial College London (UK)
University/education
University/education
Norfolk Place
London
W21PG
England
United Kingdom
"ROR" |
https://ror.org/041kmwe10 |
|---|
Funders
Funder type
Industry
Gas will be provided by BOC Ltd. Equipment and application fees will be provided by Viasys
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
