Machine perfusion preservation versus cold storage of cadaveric kidneys for transplantation
ISRCTN | ISRCTN83876362 |
---|---|
DOI | https://doi.org/10.1186/ISRCTN83876362 |
Secondary identifying numbers | TR 811/1-1 |
- Submission date
- 14/09/2005
- Registration date
- 25/01/2006
- Last edited
- 19/03/2019
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Surgery
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Prof Rutger J Ploeg
Scientific
Scientific
University Medical Center
Deparment of Surgery
PO Box 30001
Groningen
9700 RB
Netherlands
Phone | +31 (0)50 3614430 |
---|---|
r.j.ploeg@chir.umcg.nl |
Study information
Study design | Randomised controlled trial |
---|---|
Primary study design | Interventional |
Secondary study design | Randomised controlled trial |
Study setting(s) | Hospital |
Study type | Not Specified |
Scientific title | Machine perfusion preservation versus cold storage of cadaveric kidneys for transplantation |
Study acronym | Machine Preservation Trial |
Study objectives | Machine perfusion reduces the rate of delayed graft function following kidney transplantation compared to cold storage |
Ethics approval(s) | Not provided at time of registration |
Health condition(s) or problem(s) studied | Kidney insufficiency |
Intervention | One kidney of each donor is randomised to machine perfusion, the other kidney will be cold stored |
Intervention type | Procedure/Surgery |
Primary outcome measure | Delayed graft function defined by necessity of dialysis in the first 7 days post transplant |
Secondary outcome measures | 1. Decrease of creatinine 2. Rejection rates 3. Graft survival 4. Economics |
Overall study start date | 01/11/2005 |
Completion date | 31/10/2006 |
Eligibility
Participant type(s) | Patient |
---|---|
Age group | Not Specified |
Sex | Not Specified |
Target number of participants | 300 donors, 600 recipients |
Key inclusion criteria | Every deceased donor older than 15 years will be included |
Key exclusion criteria | Combined transplantations |
Date of first enrolment | 01/11/2005 |
Date of final enrolment | 31/10/2006 |
Locations
Countries of recruitment
- Germany
- Netherlands
Study participating centre
University Medical Center
Groningen
9700 RB
Netherlands
9700 RB
Netherlands
Sponsor information
Organ Recovery Systems Inc. (USA)
University/education
University/education
2570 East Devon avenue
Des Plaines
IL 60018
United States of America
lrodgers@organ-recovery.com | |
Website | http://www.organ-recovery.com |
https://ror.org/05hy2kb37 |
Funders
Funder type
Industry
Organ Recovery Systems Inc. (USA)
No information available
German Research Foundation (Deutsche Forschungsgemeinschaft) (DFG) (Germany)
No information available
Results and Publications
Intention to publish date | |
---|---|
Individual participant data (IPD) Intention to share | No |
IPD sharing plan summary | Not provided at time of registration |
Publication and dissemination plan | Not provided at time of registration |
IPD sharing plan |
Study outputs
Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
---|---|---|---|---|---|
Results article | results | 01/01/2009 | Yes | No | |
Results article | results | 01/06/2011 | Yes | No | |
Results article | results | 01/08/2018 | Yes | No |
Editorial Notes
19/03/2019: Publication reference added.