Machine perfusion preservation versus cold storage of cadaveric kidneys for transplantation

ISRCTN ISRCTN83876362
DOI https://doi.org/10.1186/ISRCTN83876362
Secondary identifying numbers TR 811/1-1
Submission date
14/09/2005
Registration date
25/01/2006
Last edited
19/03/2019
Recruitment status
No longer recruiting
Overall study status
Completed
Condition category
Surgery
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Prof Rutger J Ploeg
Scientific

University Medical Center
Deparment of Surgery
PO Box 30001
Groningen
9700 RB
Netherlands

Phone +31 (0)50 3614430
Email r.j.ploeg@chir.umcg.nl

Study information

Study designRandomised controlled trial
Primary study designInterventional
Secondary study designRandomised controlled trial
Study setting(s)Hospital
Study typeNot Specified
Scientific titleMachine perfusion preservation versus cold storage of cadaveric kidneys for transplantation
Study acronymMachine Preservation Trial
Study objectivesMachine perfusion reduces the rate of delayed graft function following kidney transplantation compared to cold storage
Ethics approval(s)Not provided at time of registration
Health condition(s) or problem(s) studiedKidney insufficiency
InterventionOne kidney of each donor is randomised to machine perfusion, the other kidney will be cold stored
Intervention typeProcedure/Surgery
Primary outcome measureDelayed graft function defined by necessity of dialysis in the first 7 days post transplant
Secondary outcome measures1. Decrease of creatinine
2. Rejection rates
3. Graft survival
4. Economics
Overall study start date01/11/2005
Completion date31/10/2006

Eligibility

Participant type(s)Patient
Age groupNot Specified
SexNot Specified
Target number of participants300 donors, 600 recipients
Key inclusion criteriaEvery deceased donor older than 15 years will be included
Key exclusion criteriaCombined transplantations
Date of first enrolment01/11/2005
Date of final enrolment31/10/2006

Locations

Countries of recruitment

  • Germany
  • Netherlands

Study participating centre

University Medical Center
Groningen
9700 RB
Netherlands

Sponsor information

Organ Recovery Systems Inc. (USA)
University/education

2570 East Devon avenue
Des Plaines
IL 60018
United States of America

Email lrodgers@organ-recovery.com
Website http://www.organ-recovery.com
ROR logo "ROR" https://ror.org/05hy2kb37

Funders

Funder type

Industry

Organ Recovery Systems Inc. (USA)

No information available

German Research Foundation (Deutsche Forschungsgemeinschaft) (DFG) (Germany)

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to shareNo
IPD sharing plan summaryNot provided at time of registration
Publication and dissemination planNot provided at time of registration
IPD sharing plan

Study outputs

Output type Details Date created Date added Peer reviewed? Patient-facing?
Results article results 01/01/2009 Yes No
Results article results 01/06/2011 Yes No
Results article results 01/08/2018 Yes No

Editorial Notes

19/03/2019: Publication reference added.